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Home > Drugs > Sulfonamides > Bactrim
Sulfonamides

Bactrim

https://themeditary.com/drug/bactrim-69.html
Medically Reviewed by Philip Thornton, DipPharm TheMediTary.Com | Reviewed: Jul 10, 2023  Additional Content by TheMediTary.Com

Generic name: sulfamethoxazole and trimethoprim [ sul-fa-meth-ox-a-zole-and-trye-meth-oh-prim ]

Drug class: Sulfonamides

Dosage form: tablet

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Bactrim ds (oral), Co-trimoxazole (monograph), Cotrim, Septra, Sulfamethoxazole and trimethoprim

Contents
Uses Warnings Before Taking Dosage Side effects Interactions FAQ
  • Bactrim (Sulfamethoxazole and trimethoprim [ sul-fa-meth-ox-a-zole-and-trye-meth-oh-prim ])-BACTRIM-400 mg / 80 mg-Green-Oval Bactrim 400 mg / 80 mg (BACTRIM)
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What is Bactrim?

Bactrim contains a combination of sulfamethoxazole and trimethoprim. Sulfamethoxazole and trimethoprim are are both antibiotics that treat different types of infection caused by bacteria.

Bactrim is a prescription medicine used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia.

To help reduce the development of drug-resistant bacteria and maintain the effectiveness of Bactrim, this medicine should be used only to treat infections that are proven, or strongly suspected, to be caused by susceptible bacteria.

Warnings

You should not use Bactrim if you have severe liver disease, kidney disease that is not being monitored, anemia caused by folic acid deficiency, if you take dofetilide, or if you have had low platelets caused by using trimethoprim or a sulfa drug.

You should not take Bactrim if you are pregnant or breastfeeding.

Use Bactrim only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not use Bactrim if you are allergic to sulfamethoxazole or trimethoprim, or if you have:

  • severe liver disease;

  • kidney disease that is not being treated or monitored;

  • anemia (low red blood cells) caused by folic acid deficiency;

  • a history of low blood platelets after taking trimethoprim or any sulfa drug; or

  • if you take dofetilide.

Sulfamethoxazole and trimethoprim may cause birth defects. Do not use Bactrim if you are pregnant. Tell your doctor if you become pregnant.

Do not breastfeed.

Bactrim should not be given to a child younger than 2 months old.

To make sure you can safely take Bactrim, tell your doctor if you have ever had:

  • kidney or liver disease;

  • a folate (folic acid) deficiency;

  • asthma or severe allergies;

  • HIV or AIDS;

  • a thyroid disorder;

  • malnourishment;

  • alcoholism;

  • an electrolyte imbalance (such as low blood sodium or high potassium);

  • porphyria, or glucose-6-phosphate dehydrogenase (G6PD) deficiency; or

  • if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

Bactrim pregnancy and breastfeeding warnings (more detail)

How should I use Bactrim

Take Bactrim exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Drink plenty of fluids to prevent kidney stones.

Antibiotic medicines can cause diarrhea. Tell your doctor if you have diarrhea that is watery or bloody.

Keep using Bactrim even if your symptoms quickly improve. Skipping doses could make your infection resistant to medication. Bactrim will not treat a viral infection (flu or a common cold).

You may need blood and urine tests, and this medicine may be stopped based on the results.

Store Bactrim at room temperature away from moisture, heat, and light. Do not refrigerate.

Detailed Bactrim dosage information
Bactrim Dosage information (more detail)

Before Taking

You should not use Bactrim if you are allergic to sulfamethoxazole or trimethoprim, or if you have:

  • severe liver disease;

  • kidney disease that is not being treated or monitored;

  • anemia (low red blood cells) caused by folic acid deficiency;

  • a history of low blood platelets after taking trimethoprim or any sulfa drug; or

  • if you take dofetilide.

Sulfamethoxazole and trimethoprim may cause birth defects. Do not use Bactrim if you are pregnant. Tell your doctor if you become pregnant.

Do not breastfeed.

Bactrim should not be given to a child younger than 2 months old.

To make sure you can safely take Bactrim, tell your doctor if you have ever had:

  • kidney or liver disease;

  • a folate (folic acid) deficiency;

  • asthma or severe allergies;

  • HIV or AIDS;

  • a thyroid disorder;

  • malnourishment;

  • alcoholism;

  • an electrolyte imbalance (such as low blood sodium or high potassium);

  • porphyria, or glucose-6-phosphate dehydrogenase (G6PD) deficiency; or

  • if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

Bactrim pregnancy and breastfeeding warnings (more detail)

Related/similar drugs

prednisone, amoxicillin, doxycycline, ciprofloxacin, cephalexin, metronidazole, azithromycin

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.

What should I avoid while using Bactrim?

Bactrim could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Bactrim side effects

Get emergency medical help if you have signs of an allergic reaction to Bactrim (hives, cough, chest pain, shortness of breath, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, joint pain, muscle aches, severe weakness, pale skin, unusual bruising, or yellowing of your skin or eyes.

Call your doctor at once if you have:

  • severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);

  • any skin rash, no matter how mild;

  • yellowing of your skin or eyes;

  • a seizure;

  • new or unusual joint pain;

  • increased or decreased urination;

  • swelling, bruising, or irritation around the IV needle;

  • increased thirst, dry mouth, fruity breath odor;

  • new or worsening cough, fever, trouble breathing;

  • high blood potassium - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement;

  • low blood sodium - headache, confusion, problems with thinking or memory, weakness, feeling unsteady; or

  • low blood cell counts - fever, chills, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.

Common Bactrim side effects may include:

  • nausea, vomiting, loss of appetite; or

  • skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Bactrim Side Effects

What other drugs will affect Bactrim?

You may need more frequent check-ups or medical tests if you also use medicine to treat depression, diabetes, seizures, or HIV.

Tell your doctor about all your current medicines. Many drugs can interact with sulfamethoxazole and trimethoprim, especially:

  • amantadine, digoxin, cyclosporine, indomethacin, leucovorin, methotrexate, procainamide, pyrimethamine;

  • an "ACE inhibitor" heart or blood presure medication (benazepril, enalapril, lisinopril, quinapril, ramipril, and others); or

  • a diuretic or "water pill".

This list is not complete and many other drugs may interact with sulfamethoxazole and trimethoprim. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What to Expect

You should feel better within a few days of starting on Bactrim. Let your doctor know if your condition doesn’t improve or worsens.

Keep taking this medicine even if you feel better. Stopping Bactrim too soon can cause your infection to come back.

Additional Dosage Information

Your dosage will depend on your age, your medical condition, the formulation you use, and other factors.

Follow your doctor’s instructions carefully when using this medicine.

Secondary Uses

Bactrim may be used to treat other types of infections that aren’t listed in this guide.

Popular FAQ

Does Bactrim cause headaches?
Can I drink alcohol when taking sulfamethoxazole / trimethoprim DS?
What drugs should be avoided with a sulfa allergy?
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More FAQ

Smelling an odd citrus/perfume smell while on sulfameth/trimethoprim?
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More about Bactrim (Sulfamethoxazole and trimethoprim [ sul-fa-meth-ox-a-zole-and-trye-meth-oh-prim ])

Dosage information
Bactrim Side Effects
Patient tips
During pregnancy
Bactrim Prescribing Information
Drug images
Side effects
Drug class: Sulfonamides

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Uses Warnings Before Taking Dosage Side effects Interactions FAQ
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