Univasc is an ACE inhibitor. ACE stands for angiotensin converting enzyme.

Univasc is used to treat high blood pressure (hypertension).

Univasc may also be used for purposes not listed in this medication guide.

Do not use if you are pregnant. If you become pregnant, stop taking Univasc and tell your doctor right away.

If you have diabetes, do not use Univasc together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo).

Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take Univasc in larger or smaller amounts or for longer than recommended.

Univasc is usually taken 1 hour before meals.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking Univasc. This can lead to very low blood pressure, electrolyte disorders, or kidney failure.

While using Univasc, you may need frequent blood tests at your doctor's office. Your blood pressure will need to be checked often.

If you need surgery, tell the surgeon ahead of time that you are using Univasc. You may need to stop using the medicine for a short time.

If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture and heat.

You should not use this medication if you are allergic to Univasc or similar medications--benazepril, captopril, enalapril, fosinopril, lisinopril, perindopril, quinapril, ramipril, or trandolapril.

If you have diabetes, do not use Univasc together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo).

You may also need to avoid taking Univasc with aliskiren if you have kidney disease.

To make sure Univasc is safe for you, tell your doctor if you have:

• kidney disease (or if you are on dialysis);

• liver disease;

• heart disease or congestive heart failure;

• if you are on a low-salt diet; or

• a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.

Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Univasc can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

It is not known whether moexipril passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Do not use salt substitutes or potassium supplements while taking Univasc, unless your doctor has told you to.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Get emergency medical help if you have signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Univasc may cause serious side effects. Call your doctor at once if you have:

• a light-headed feeling, like you might pass out;

• sudden weakness or ill feeling, fever, chills, sore throat, painful mouth sores, cough, trouble breathing;

• little or no urinating; or

• high potassium--nausea, slow or unusual heart rate, weakness, loss of movement.

Common side effects of Univasc may include:

• cough, runny or stuffy nose;

• headache, dizziness, tired feeling;

• increased urination;

• diarrhea;

• muscle pain; or

• mild skin itching or rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tell your doctor about all your current medicines and any you start or stop using, especially:

• lithium;

• a blood thinner such as warfarin, Coumadin; or

• a diuretic or "water pill";

• gold injections to treat arthritis;

• NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others;

• a potassium supplement such as K-Dur, Klor-Con; or

• salt substitutes that contain potassium.

This list is not complete. Other drugs may interact with moexipril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.