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Home > Drugs > Azole antifungals > Vivjoa
Azole antifungals

Vivjoa

https://themeditary.com/drug/vivjoa-3626.html
Medically Reviewed by Judith Stewart, BPharm TheMediTary.Com | Reviewed: Jul 14, 2023  Additional Content by TheMediTary.Com

Generic name: oteseconazole

Drug class: Azole antifungals

Dosage form: capsules

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Oteseconazole

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Vivjoa?

  • Vivjoa is a prescription antifungal medicine used to reduce the risk of vaginal yeast infections that keep coming back (recurrent vulvovaginal candidiasis, RVVC) in females with a history of RVVC.
  • Vivjoa should only be taken by females who are not pregnant and who are NOT able to become pregnant.

It is not known if this medicine is safe and effective in females who have not had their first menstrual period.

How should I take Vivjoa

There are two recommended Vivjoa dosage regimens: one with Vivjoa only, and the other with Vivjoa and fluconazole. Your doctor will advise the best dosage regimen for you.

For the Vivjoa-only Dosage Regimen:

  • Take Vivjoa exactly as your doctor tells you to take it. Talk to your doctor if you have any questions.
    • On Day 1: Take 600 mg (four capsules as a single dose), by mouth then,
    • On Day 2: Take 450 mg (three capsules as a single dose), by mouth then,
    • On Day 14: Take 150 mg (one capsule) one time a week (every 7 days) by mouth for 11 weeks.
  • Take Vivjoa capsules by mouth with food. Swallow the capsules whole. Do not chew, crush, dissolve, or open the capsules.

For the Vivjoa-fluconazole Dosage Regimen:

  • Take fluconazole and Vivjoa exactly as your doctor tells you to take it. Talk to your doctor if you have any questions.
    • On Day 1, Day 4, and Day 7: Take 1 fluconazole tablet (150 mg) by mouth, then
    • On Days 14 through 20: Take 1 Vivjoa capsule (150 mg) by mouth 1 time each day for 7 days, then
    • On Day 28: Take 1 Vivjoa capsule (150 mg) by mouth 1 time each week (every 7 days) for 11 weeks.
  • Take Vivjoa capsules by mouth with food. Swallow the capsules whole. Do not chew, crush, dissolve, or open the capsules.

Dosing information

Usual Adult Dosage for Vulvovaginal Candidiasis

Vivjoa-Only Regimen

  • On Day 1: Administer Vivjoa 600 mg (as a single dose), then
  • On Day 2: Administer 450 mg (as a single dose), then
  • Beginning on Day 14: Administer 150 mg once a week (every 7 days) for 11 weeks (Weeks 2 through 12).

Fluconazole/Vivjoa Dosage Regimen

  • On Day 1, Day 4, and Day 7: Administer fluconazole 150 mg orally, then
  • On Days 14 through 20: Administer Vivjoa 150 mg once daily for 7 days, then
  • Beginning on Day 28: Administer Vivjoa 150 mg once a week (every 7 days) for 11 weeks (Weeks 4 through 14).

- Use: to reduce the incidence of recurrent vulvovaginal candidiasis (RVVC) in females with a history of RVVC who are NOT of reproductive potential.

Detailed Vivjoa dosage information
Vivjoa Dosage information (more detail)

Before Taking

You should not take Vivjoa if you:

  • Are able to become pregnant.
  • Are pregnant or plan to become pregnant. Vivjoa may harm your unborn baby. Tell your doctor if you are pregnant, think you might be pregnant, or plan to become pregnant.
  • Are breastfeeding or plan to breastfeed. It is not known if Vivjoa passes into your breastmilk.
  • Are allergic to oteseconazole or any of the ingredients. See the end of this page for a complete list of ingredients.
Vivjoa pregnancy and breastfeeding warnings (more detail)

Before taking Vivjoa

Before you start treatment, tell your doctor about all of your medical conditions, including if you:

  • have kidney problems
  • have liver problems

Vivjoa side effects

  • Females who are pregnant, are able to become pregnant, and females who are breastfeeding should not take Vivjoa.

The most common side effects are headache and nausea.

These are not all the possible side effects. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Vivjoa Side Effects

What other drugs will affect Vivjoa?

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your doctor if you take medicines called breast cancer resistance protein (BCRP) transporter substrates, including:

  • rosuvastatin
  • prazosin
  • glyburide
  • cimetidine
  • sulfasalazine
  • zidovudine
  • lamivudine.

Ask your doctor or pharmacist if you are not sure. Taking Vivjoa (a BCRP inhibitor) with BCRP transporter substrates may increase the risk of side effects with these medicines.

Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

More about Vivjoa (Oteseconazole)

Dosage information
Vivjoa Side Effects
During pregnancy
Vivjoa Prescribing Information
Drug images
Side effects
Drug class: Azole antifungals

Related treatment guides

Vaginal Yeast Infection
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Contents
Uses Warnings Before Taking Dosage Side effects Interactions
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