Xepi is an antibiotic medicine used to treat a skin infection called impetigo.

Xepi is for use in adults and children who are at least 2 months old.

Xepi may also be used for purposes not listed in this medication guide.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not take by mouth. Topical medicine is for use only on the skin.

Apply a thin layer of ozenoxacin topical to the affected skin.

Wash your hands after applying Xepi, unless you are treating the skin on your hands.

You may cover the treated skin with a clean bandage or gauze dressing.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication.

Call your doctor if your symptoms do not improve after 3 days.

Store at room temperature away from moisture and heat.

Tell your doctor if you are pregnant or breast-feeding.

Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

An overdose of Xepi is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Avoid getting Xepi in your eyes, nose, mouth, or vagina.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Xepi may cause serious side effects. Call your doctor at once if you have:

• any signs of a new skin infection (redness, warmth, swelling, oozing).

Common side effects of Xepi may include:

• skin redness;

• itching; or

• skin dryness, peeling, or flaking.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.