Note: This document contains side effect information about aspirin. Some dosage forms listed on this page may not apply to the brand name Durlaza.

Applies to aspirin: oral capsules, oral gum, oral tablets, rectal suppositories.

Side effects include:

Minor upper GI symptoms (dyspepsia).

For Healthcare Professionals

Applies to aspirin: compounding powder, oral capsule, oral capsule extended release, oral delayed release capsule, oral delayed release tablet, oral gum, oral powder for reconstitution, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet dispersible, oral tablet extended release, rectal suppository.

Gastrointestinal

Common (1% to 10%): Dyspepsia,

Frequency not reported: GI bleeding, ulceration, perforation, nausea, vomiting, pancreatitis, gastric irritation, GI erosions, gastritis, melena, hematemesis, gingival bleeding^[Ref]

Renal

Frequency not reported: Interstitial nephritis, papillary necrosis, renal insufficiency and failure^[Ref]

Hematologic

Common (1% to 10%): Increased bleeding tendencies

Rare (0.01% to 0.1%): Aplastic anemia agranulocytosis, thrombocytopenia

Frequency not reported: Prolongation of prothrombin time, disseminated intravascular coagulation, coagulopathy, antepartum and postpartum bleeding, anemia^[Ref]

Hypersensitivity

Rare (0.01% to 0.1%): Anaphylactic reactions including shock

Frequency not reported: Urticaria, angioedema, skin rashes^[Ref]

Dermatologic

Uncommon (0.1% to 1%): Urticaria

Rare (0.01% to 0.1%): Steven-Johnson syndrome, Lyell's syndrome, erythema nodosum, erythema multiforme

Frequency not reported: Purpura, hives^[Ref]

Hepatic

Frequency not reported: Transient elevations of hepatic enzymes, hepatitis, Reye's syndrome, hepatic insufficiency^[Ref]

Metabolic

Frequency not reported: Thirst, dehydration, hyperkalemia, metabolic acidosis, respiratory alkalosis, hypoglycemia, hyperglycemia, hyperuricemia, salt and water retention^[Ref]

Cardiovascular

Rare (0.01% to 0.1%): Hemorrhagic vasculitis

Frequency not reported: Dysrhythmias, hypotension, tachycardia^[Ref]

Nervous system

Frequency not reported: Cerebral edema, coma headache, subdural or intracranial hemorrhage, seizures, lethargy, dizziness^[Ref]

Other

Frequency not reported: Fever, hypothermia, hearing loss, tinnitus (at high doses), hearing disturbances^[Ref]

Musculoskeletal

Frequency not reported: Rhabdomyolysis^[Ref]

Respiratory

Frequency not reported: Hyperpnea, pulmonary edema, tachypnea, epistaxis, dyspnea, bronchospasm, asthma^[Ref]

General

The more commonly experienced adverse effects include indigestion, dyspepsia, bleeding, and bruising.^[Ref]

Genitourinary

Rare (0.01% to 0.1%): Menorrhagia

Frequency not reported: Proteinuria^[Ref]

Psychiatric

Frequency not reported: Agitation, confusion^[Ref]