Applies to eflornithine topical: topical cream.
Other side effects
Some side effects of eflornithine topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Acne
- stinging skin
Less common
- Burning or bleeding skin
- chapped, red lips
- chronic acne
- hair bumps
- numbness
- rash
- reddening of skin
- swelling of lips
- tingling skin
For Healthcare Professionals
Applies to eflornithine topical: topical cream.
General
The most frequently reported side effects were dermatologic in nature and included acne and pseudofolliculitis barbae.[Ref]
Dermatologic
Very common (10% or more): Acne (up to 21.3 %), pseudofolliculitis barbae (up to 16.3%)
Common (1% to 10%): Stinging skin, burning skin, dry skin, pruritus, erythema, tingling skin, skin irritated, rash, alopecia
Uncommon (0.1% to 1%): Ingrown hair, papular rash, skin bleeding, eczema, contact dermatitis, hair texture abnormal, hair growth abnormal, skin hypopigmentation, skin soreness
Rare (less than 0.1%): Rosacea, seborrheic dermatitis, maculopapular rash, skin cyst, vesiculobullous rash, skin disorder, hirsutism, skin tightness[Ref]
Nervous system
Common (1% to 10%): Headache, dizziness
Frequency not reported: Numbness[Ref]
Gastrointestinal
Common (1% to 10%): Dyspepsia
Uncommon (0.1% to 1%): Nausea, cheilitis, numb lip
Frequency not reported: Swollen lip[Ref]
Cardiovascular
Uncommon (0.1% to 1%): Flushing[Ref]
Other
Common (1% to 10%): Folliculitis
Uncommon (0.1% to 1%): Facial edema, asthenia, vertigo, mouth edema, herpes simplex, furunculosis[Ref]
Metabolic
Uncommon (0.1% to 1%): Anorexia[Ref]
Oncologic
Rare (less than 0.1%): Skin neoplasm[Ref]
