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Home > Drugs > Eflornithine (monograph)
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Eflornithine (monograph)

https://themeditary.com/drug/eflornithine-monograph-6130.html
Medically Reviewed by Oluni Odunlami, MD TheMediTary.Com | Reviewed: Aug 13, 2023  Additional Content by TheMediTary.Com

Generic name: vaniqa

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Vaniqa, Eflornithine topical

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

What is Eflornithine (monograph)?

Introduction

Hair growth retardant.

Uses for Eflornithine

Reduction of Unwanted Facial Hair

Reduction of unwanted facial hair in women.

Eflornithine Dosage and Administration

General

  • Marked improvement may occur after 8 weeks of therapy. Hair growth usually returns to baseline levels 8 weeks after discontinuing therapy.

Administration

Topical Administration

Apply to skin as a 13.9% cream.

Apply only to affected areas of the face and adjacent involved areas under the chin; not intended for oral, ophthalmic, or intravaginal use.

Apply a thin film and rub in thoroughly.

Do not wash treated areas for at least 4 hours after application.

Continue hair removal techniques (e.g., plucking, tweezing, cutting, shaving), as needed, throughout treatment. Do not apply cream for at least 5 minutes after hair removal.

May apply cosmetic products and sunscreens after cream has dried.

Dosage

Available as eflornithine hydrochloride; dosage expressed in terms of the salt.

Adults

Reduction of Unwanted Facial Hair
Topical

Apply a thin film twice daily at least 8 hours apart (or as directed by clinician).

If skin irritation or intolerance develops, reduce application frequency to once daily. If irritation continues, discontinue therapy.

Detailed Eflornithine topical dosage information

Related/similar drugs

spironolactone, Aldactone, Vaniqa, flutamide, Florexa, Eulexin

Warnings

Contraindications

  • Known hypersensitivity to eflornithine or any ingredient in the formulation.

Warnings/Precautions

Sensitivity Reactions

Hypersensitivity Reactions

Discontinue therapy if hypersensitivity reactions occur.

General Precautions

Dermatologic Effects

Possible transient stinging or burning if applied to abraded or broken skin.

Skin irritation may occur in susceptible patients or in those using higher than recommended dosages.

Specific Populations

Pregnancy

Category C.

Lactation

Not known whether eflornithine is distributed into milk. Caution if used in nursing women.

Pediatric Use

Safety and efficacy not established in children <12 years of age.

Geriatric Use

No substantial differences in safety relative to younger adults.

Common Adverse Effects

Burning, stinging, and/or tingling skin; erythema; rash.

How should I use Eflornithine (monograph)

General

  • Marked improvement may occur after 8 weeks of therapy. Hair growth usually returns to baseline levels 8 weeks after discontinuing therapy.

Administration

Topical Administration

Apply to skin as a 13.9% cream.

Apply only to affected areas of the face and adjacent involved areas under the chin; not intended for oral, ophthalmic, or intravaginal use.

Apply a thin film and rub in thoroughly.

Do not wash treated areas for at least 4 hours after application.

Continue hair removal techniques (e.g., plucking, tweezing, cutting, shaving), as needed, throughout treatment. Do not apply cream for at least 5 minutes after hair removal.

May apply cosmetic products and sunscreens after cream has dried.

Dosage

Available as eflornithine hydrochloride; dosage expressed in terms of the salt.

Adults

Reduction of Unwanted Facial Hair
Topical

Apply a thin film twice daily at least 8 hours apart (or as directed by clinician).

If skin irritation or intolerance develops, reduce application frequency to once daily. If irritation continues, discontinue therapy.

Detailed Eflornithine topical dosage information

Related/similar drugs

spironolactone, Aldactone, Vaniqa, flutamide, Florexa, Eulexin
Eflornithine (monograph) Dosage information (more detail)

More about Eflornithine (monograph) (Vaniqa)

Dosage information
Eflornithine (monograph) Side Effects
During pregnancy
Drug images
Side effects
Breastfeeding Warnings
Drug class: Drugs

Related treatment guides

Hirsutism
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Contents
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