Note: This document contains side effect information about adapalene / benzoyl peroxide topical. Some dosage forms listed on this page may not apply to the brand name Epiduo Forte.
Summary
Common side effects of Epiduo Forte include: burning sensation of skin, desquamation, stinging of the skin, erythema of skin, and xeroderma. Continue reading for a comprehensive list of adverse effects.
Applies to adapalene/benzoyl peroxide topical: topical application gel/jelly, topical application pad.
Serious side effects of Epiduo Forte
Along with its needed effects, adapalene/benzoyl peroxide topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking adapalene / benzoyl peroxide topical:
More common
- Dryness and peeling of the skin
- flushing or redness of the skin
- unusually warm skin
Less common
- Blistering, burning, crusting, or flaking of the skin
- burning, itching, redness, skin rash, swelling, or soreness at the application site
- scaling, severe redness, or swelling of the skin
Incidence not known
- Skin pain
- sunburn
Other side effects of Epiduo Forte
Some side effects of adapalene / benzoyl peroxide topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- Burning, dry, or itching eyes
- change in the color of the treated skin
- discharge or excessive tearing
- redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
- skin rash, encrusted, scaly, and oozing
- swelling of the face
For Healthcare Professionals
Applies to adapalene / benzoyl peroxide topical: topical gel.
General
The most commonly reported side effects include irritative contact dermatitis, burning sensation, and dry skin.[Ref]
Dermatologic
Common (1% to 10%): Irritative contact dermatitis, dry skin/dryness, skin irritation, erythema, skin exfoliation/scaling
Uncommon (0.1% to 1%): Sunburn, pruritus, atopic dermatitis, eczema
Frequency not reported: Skin pain/stinging pain
Postmarketing reports: Allergic contract dermatitis, blisters/vesicles, skin discoloration, rash[Ref]
Local
Common (1% to 10%): Application site burning, application site irritation[Ref]
Nervous system
Common (1% to 10%): Burning sensation/skin burning sensation[Ref]
Ocular
Postmarketing reports: Eyelid edema, conjunctivitis[Ref]
Respiratory
Postmarketing reports: Throat tightness[Ref]
Other
Postmarketing reports: Swelling face[Ref]
