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Home > Drugs > Benzodiazepines > Flurazepam > Flurazepam Side Effects
Benzodiazepines

Flurazepam Side Effects

Summary

Commonly reported side effects of flurazepam include: drowsiness. Other side effects include: dizziness, vertigo, insomnia, confusion, headache, and irritability. Continue reading for a comprehensive list of adverse effects.

Applies to flurazepam: oral capsule.

Warning

Oral route (Capsule)

Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing for patients with inadequate alternative treatment options. Limit dosages and durations to the minimum required and follow patients for signs and symptoms of respiratory depression and sedation.

Serious side effects of Flurazepam

Along with its needed effects, flurazepam may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking flurazepam:

Rare

  • Black, tarry stools
  • blurred vision
  • chest pain
  • chills
  • confusion
  • cough
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • feeling like you will pass out
  • fever
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • painful or difficult urination
  • slurred speech
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • sweating
  • swollen glands
  • unusual bleeding or bruising
  • unusual tiredness or weakness

Incidence not known

  • Change in consciousness
  • clumsy movement, moving from side to side
  • confusion about identity, place, and time
  • falling
  • fast, irregular, pounding, or racing heartbeat or pulse
  • loss of consciousness
  • shakiness and unsteady walk
  • unsteadiness, trembling, or other problems with muscle control or coordination
  • unusual drowsiness, dullness, tiredness, weakness or feeling of sluggishness

Other side effects of Flurazepam

Some side effects of flurazepam may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

  • Bitter taste
  • blurred vision
  • burning eyes
  • difficulty in focusing
  • discouragement
  • dry mouth
  • false or unusual sense of well-being
  • feeling of warmth
  • feeling sad or empty
  • hallucinations
  • increased watering of the mouth
  • itching skin or skin rash
  • loss of appetite
  • loss of interest or pleasure
  • mood or mental changes
  • nightmares
  • redness of the face, neck, arms and occasionally, upper chest
  • restlessness
  • sweating
  • trouble concentrating
  • trouble sleeping
  • unusual excitement, nervousness, restlessness, or irritability
  • weight loss

Incidence not known

  • Constipation
  • diarrhea
  • fear
  • headache
  • heartburn
  • joint pain
  • nausea
  • stomach upset
  • talkativeness
  • vomiting

For Healthcare Professionals

Applies to flurazepam: oral capsule.

Nervous system

Common (1% to 10%): Reduced alertness, confusion, headache, dizziness, ataxia

Rare (less than 0.1%): Difficulty in focusing, faintness, slurred speech, confusion, restlessness, vertigo

Frequency not reported: CNS-depressant effects, next-day impairment, nervousness, talkativeness, drowsiness, staggering[Ref]

Psychiatric

Common (1% to 10%): Numbed emotions

Rare (less than 0.1%): Euphoria, depression, hallucinations

Frequency not reported: Withdrawal syndrome, abnormal thinking, behavior changes, complex behaviors, worsening of depression, apprehension, irritability[Ref]

Other

Common (1% to 10%): Fatigue

Frequency not reported: Weakness[Ref]

Gastrointestinal

Rare (less than 0.1%): Dry mouth, bitter taste, excessive salivation

Frequency not reported: Heartburn, upset stomach, nausea, vomiting, diarrhea, constipation, gastrointestinal pain[Ref]

Hepatic

Rare (less than 0.1%): Elevated SGOT/SGPT, total and direct bilirubin elevations, elevated alkaline phosphatase

Frequency not reported: Jaundice[Ref]

Hypersensitivity

Very rare (less than 0.01%): Severe anaphylactic/anaphylactoid reactions[Ref]

Cardiovascular

Frequency not reported: Palpitation, chest pain[Ref]

Dermatologic

Rare (less than 0.1%): Sweating, pruritus, skin rash[Ref]

General

The most commonly reported side effects were headache, dizziness, muscle weakness, ataxia, and double vision.[Ref]

Genitourinary

Frequency not reported: Genitourinary complaints, changes in libido, urinary retention[Ref]

Hematologic

Rare (less than 0.1%): Leukopenia, granulocytopenia

Frequency not reported: Blood dyscrasias[Ref]

Metabolic

Rare (less than 0.1%): Anorexia[Ref]

Musculoskeletal

Common (1% to 10%): Muscle weakness

Frequency not reported: Body/joint pain[Ref]

Ocular

Common (1% to 10%): Double vision

Rare (less than 0.1%): Blurred vision, burning eyes

Frequency not reported: Visual disturbance[Ref]

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