Summary

Commonly reported side effects of fomepizole include: headache and nausea. Other side effects include: dizziness. Continue reading for a comprehensive list of adverse effects.

Applies to fomepizole: parenteral injection concentrate for iv infusion.

Side effects include:

Headache, nausea, dizziness, increased drowsiness, bad/metallic taste.

For Healthcare Professionals

Applies to fomepizole: intravenous solution.

General

The most common adverse events were headache, nausea, dizziness, increased drowsiness, and bad taste/metallic taste.^[Ref]

Gastrointestinal

Very common (10% or more): Nausea (11%)

Common (1% to 10%): Abdominal pain, vomiting, diarrhea, dyspepsia, heartburn^[Ref]

Nervous system

Very common (10% or more): Headache (14%)

Common (1% to 10%): Dizziness, increased drowsiness, bad taste/metallic taste, lightheadedness, seizure, agitation, feeling drunk, vertigo, nystagmus, anxiety, "felt strange", decreased environmental awareness, abnormal smell, roar in ear^[Ref]

Other

Common (1% to 10%): Fever, multiorgan system failure, hangover, speech/visual disturbances^[Ref]

Cardiovascular

Common (1% to 10%): Sinus bradycardia/bradycardia, phlebosclerosis, tachycardia, phlebitis, shock, hypotension^[Ref]

Hematologic

Common (1% to 10%): Eosinophilia/hypereosinophilia, lymphangitis, disseminated intravascular coagulation, anemia^[Ref]

Hepatic

Common (1% to 10%): Transient transaminitis^[Ref]

Local

Common (1% to 10%): Pain during injection, inflammation at injection site, application site reaction^[Ref]

Genitourinary

Common (1% to 10%): Anuria^[Ref]

Respiratory

Common (1% to 10%): Hiccups, pharyngitis^[Ref]

Ocular

Common (1% to 10%): Transient blurred vision^[Ref]

Dermatologic

Common (1% to 10%): Facial flush, rash^[Ref]

Musculoskeletal

Common (1% to 10%): Lumbalgia/backache^[Ref]

Metabolic

Common (1% to 10%): Decreased appetite