Note: This document contains side effect information about homatropine ophthalmic. Some dosage forms listed on this page may not apply to the brand name Homatropaire.
Applies to homatropine ophthalmic: ophthalmic solution.
Side effects include:
Elevated IOP, transient stinging, burning. With prolonged administration, local irritation (characterized by follicular conjunctivitis, vascular congestion, edema, exudate, and eczematoid dermatitis ), thirst, dry mouth, increased light sensitivity of eyes.
For Healthcare Professionals
Applies to homatropine ophthalmic: compounding powder, ophthalmic solution.
General
The most frequently reported side effects were transient stinging/burning upon instillation and increased sensitivity to light.[Ref]
Ocular
Common (1% to 10%): Transient burning, transient stinging, increased sensitivity to light
Uncommon (0.1% to 1%): Eye irritation
Rare (0.01% to 0.1%): Local irritation, vascular congestion, edema, exudates, eczematoid dermatitis, follicular conjunctivitis
Postmarketing reports: Conjunctivitis, photophobia, mydriasis prolonged, eye pain, eye edema, eye discharge, eye irritation, ocular hyperemia[Ref]
Gastrointestinal
Rare (0.01% to 0.1%): Thirst, dryness of mouth
Frequency not reported: Abdominal distention infants, gastrointestinal motility diminished, salivary secretion decreased, sweat gland secretion decreased[Ref]
Nervous system
Frequency not reported: Ataxia, incoherent speech, hyperactivity, seizure, unusual drowsiness
Postmarketing reports: Somnolence[Ref]
Psychiatric
Frequency not reported: Restlessness, hallucination, disorientation, failure to recognize people
Postmarketing reports: Confusion[Ref]
Genitourinary
Frequency not reported: Urinary retention[Ref]
Respiratory
Frequency not reported: Secretion decreased in pharynx/bronchi/nasal passages, rapidly progressive respiratory depression[Ref]
Other
Frequency not reported: Hyperpyrexia[Ref]
Cardiovascular
Frequency not reported: Tachycardia, vasodilation, hypotension
Postmarketing reports: Heart rate increased[Ref]
Dermatologic
Frequency not reported: Skin rash[Ref]
