Note: This document contains side effect information about deoxycholic acid. Some dosage forms listed on this page may not apply to the brand name Kybella.
Applies to deoxycholic acid: subcutaneous solution.
Serious side effects of Kybella
Along with its needed effects, deoxycholic acid (the active ingredient contained in Kybella) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking deoxycholic acid:
Less common
- Headache
- muscle weakness in the face
- pain in the mouth or throat
- pounding in the ears
- slow or fast heartbeat
- trouble swallowing
- uneven smile
Incidence not known
- Blue-green to black skin discoloration
- cracking of the skin
- fainting
- neck pain
- pain, redness, or sloughing of the skin at the injection site
- swollen, painful, or tender lymph glands in the neck
Other side effects of Kybella
Some side effects of deoxycholic acid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Bleeding, blistering, bruising, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, rash, scarring, soreness, stinging, swelling, tenderness, tightness of the skin, tingling, or warmth at the injection site
Less common
- Nausea
Incidence not known
- Hair loss at the injection site
For Healthcare Professionals
Applies to deoxycholic acid: subcutaneous solution.
Gastrointestinal
Common (1% to 10%): Oropharyngeal pain, nausea, dysphagia[Ref]
Local
Very common (10% or more): Injection site reactions (96%): edema/swelling (87%), hematoma/bruising (72%), pain (70%), numbness (66%), erythema (27%), induration (23%), paresthesia (14%), nodule (13%), pruritus (12%),
Common (1% to 10%): Injection site reactions: skin tightness, site warmth, marginal mandibular nerve injury
Frequency not reported: Injection site reactions: hemorrhage, discoloration, urticaria[Ref]
Cardiovascular
Common (1% to 10%): Hypertension[Ref]
Hematologic
Frequency not reported: Lymphadenopathy[Ref]
Musculoskeletal
Frequency not reported: Neck pain[Ref]
Nervous system
Common (1% to 10%): Headache
Frequency not reported: Pre-syncope/syncope[Ref]
