Applies to latanoprost/netarsudil ophthalmic: ophthalmic solution.
Serious side effects
Along with its needed effects, latanoprost/netarsudil ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking latanoprost / netarsudil ophthalmic:
More common
- Bloody eye
- blurred vision or any other change in vision
- eye redness, irritation, or pain
- redness of the eye
Rare
- Body aches or pain
- burning and stinging of the eye
- change in color vision
- chills
- cough
- diarrhea
- difficulty in breathing
- difficulty seeing at night
- difficulty swallowing
- dizziness
- dry eye
- ear congestion
- excessive tearing
- eyelid discomfort, swelling, or redness
- fast heartbeat
- fever
- general feeling of discomfort or illness
- headache
- hives, itching, skin rash
- increased sensitivity of the eyes to sunlight
- joint pain
- loss of appetite
- loss of voice
- nausea
- painful irritation of the clear front part of the eye
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- runny or stuffy nose
- shivering
- sneezing
- sore throat
- sweating
- tightness in the chest
- trouble sleeping
- unusual tiredness or weakness
- vomiting
Other side effects
Some side effects of latanoprost / netarsudil ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Eye itching
- pain and discomfort at the instillation site
Less common
- Increase in brown color in the colored part of the eye
- redness of the white part of the eyes or the inside of the eyelids
Rare
- Back pain
- crusting in the corner of the eye
- difficulty in moving
- discoloration of the white part of the eye
- feeling of having something in the eye
- joint pain or swelling
- muscle pain, cramps, or stiffness
For Healthcare Professionals
Applies to latanoprost / netarsudil ophthalmic: ophthalmic solution.
General
The most commonly reported side effects included conjunctival hyperemia, instillation site pain, and corneal verticillata.[Ref]
Ocular
Very common (10% or more): Conjunctival hyperemia (up to 59%), corneal verticillata (up to 15%), conjunctival hemorrhage (up to 11%)
Common (1% to 10%): Blurred vision, eye pruritus, increased lacrimation, visual acuity reduced
Latanoprost:
-Frequency not reported: Dry eye, erythema of the eyelid, excessive tearing, eye pain, eyelid discomfort, eyelid edema, eyelid margin crusting, foreign body sensation, increased pigmentation of the iris, photophobia, punctate keratitis
Netarsudil:
-Frequency not reported: Corneal staining, erythema of eyelid, increased lacrimation[Ref]
Dermatologic
Latanoprost:
-Frequency not reported: Itching, rash[Ref]
Nervous system
Latanoprost:
-Frequency not reported: Burning[Ref]
Hypersensitivity
Latanoprost:
-Frequency not reported: Allergic reactions[Ref]
Immunologic
Latanoprost:
-Frequency not reported: Influenza[Ref]
Local
Very common (10% or more): Instillation site pain (up to 20%)
Common (1% to 10%): Instillation site discomfort
Netarsudil:
-Frequency not reported: Instillation site erythema[Ref]
Musculoskeletal
Latanoprost:
-Frequency not reported: Arthralgia, back pain, myalgia[Ref]
Other
Latanoprost:
-Frequency not reported: Stinging[Ref]
Respiratory
Latanoprost:
-Frequency not reported: Nasopharyngitis, upper respiratory tract infection[Ref]
