Applies to macimorelin: oral granule for reconstitution.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• a light-headed feeling, like you might pass out;

• slow heartbeats;

• shortness of breath; or

• fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out).

Common side effects may include:

• headache, dizziness;

• hunger, nausea, diarrhea;

• increased sweating, feeling hot;

• feeling tired;

• changes in your sense of taste; or

• cold symptoms such as stuffy nose, sinus pain, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to macimorelin: oral granule for reconstitution.

Cardiovascular

Common (1% to 10%): Sinus bradycardia^[Ref]

Gastrointestinal

Common (1% to 10%): Dysgeusia, nausea, diarrhea^[Ref]

Nervous system

Common (1% to 10%): Dizziness, headache^[Ref]

Immunologic

Common (1% to 10%): Upper respiratory tract infection, nasopharyngitis^[Ref]

Other

Common (1% to 10%): Fatigue, feeling hot^[Ref]

Metabolic

Common (1% to 10%): Hunger^[Ref]

Dermatologic

Common (1% to 10%): Hyperhidrosis^[Ref]