Answers by TheMediTary.Com - Last updated: 13-Jul-2023
"Usual Adult Dose for Otitis Media:
250 mg to 500 mg orally 3 times a day for 10 to 14 days; alternatively, 500 to 875 mg orally twice a day may be administered"
Amoxicillin is usually taken three times a day, but may be given twice a day.
https://www.drugs.com/dosage/amoxicillin.html#Usual_Adult_Dose_for_Otitis_Media
Amoxicillin can be taken with or without food - food has no effect on the medicine.