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Home > Medical Answers > Does duloxetine withdrawal cause a “pins and needles” feeling in hands or feet?

Does duloxetine withdrawal cause a “pins and needles” feeling in hands or feet?

Posted on 16-Aug-2023 - Last updated: 16-Aug-2023

My partner was placed on 120mg of duloxetine for pins and needles or tingling feelings and numbness in her feet due to idiopathic neuropathy by a neurologist. After 1 year on this med with no impact on the pins and needles feeling or numbness the doctor said she should taper off. She initially cut the dose down to 60 mg every other day and 120 mg on the other days. After two weeks, she went to 60 mg every day for the next two weeks. This went okay, not great but not horrible. She had some diarrhea and flu-like symptoms. Mostly she was just exhausted and stayed in bed watching tv. After the 2 weeks of 60 mg each day, she started taking 60 mg every other day. The plan was to do this for two weeks, then stop completely. On the days she didn’t take the duloxetine 60 mg, she said the pins and needles feeling in her feet got worse. We talked to the doctor and he said that was a sign the drug was working and reinstated her to 120 mg a day. My research has shown that an increase in the pins and needles feeling might be withdrawal symptoms from the drug? Asked the doctor and he said no. The only withdrawal symptom anyone should ever have is mild stomach upset. I thought we should continue with the taper and see if once she was completely off duloxetine the pins and needles feeling went back to her normal level. My question to this group is has anyone experienced pins and needles or tingling feeling in their hands or feet during their process to taper off of duloxetine? Thanks!

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