Answers by TheMediTary.Com - Last updated: 12-Jul-2023
It may take up to 6 to 8 weeks for the full effects of Cymbalta to be seen, although some improvement in symptoms, such as sleep, energy, or appetite may show an improvement in 1-2 weeks. Symptoms such as depressed mood and lack of interest in activities may take the full 6-8 weeks to resolve. When Cymbalta is used for pain, it generally improves within two weeks.
Side effects such as include feeling sick, a dry mouth, headache, constipation, or feeling sleepy may occur early on, but these are usually mild and go away after a couple of weeks.