Key Points

• Entyvio (vedolizumab) is an expensive intravenous (IV) medication used for ulcerative colitis or Crohn‘s disease. According to the manufacturer, the list price for a 30-day supply of Entyvio is $3,363.82 or $40,365.84 per year.
• Patients typically receive 300 mg infusions every 2 months in the maintenance phase so this would cost around $6,700 per infusion. However, most patients do not pay this price.
• Prices listed are for cash paying customers. Patients with private insurance or government sponsored plans will have different costs based on formulary coverage, copay tiers, or any discounts.
• You may also be eligible for EntyvioConnect, the patient financial assistance program from Takeda Pharmaceuticals at 1-844-368-9846.

Entyvio is approved by the FDA to treat adults with moderate to severe ulcerative colitis or Crohn‘s disease, two inflammatory bowel diseases that affect your digestive tract. Entyvio is classified as an integrin receptor antagonist that works by blocking certain cells to help decrease inflammation in the gastrointestinal tract.

Entyvio is given as a 300 mg intravenous (IV) infusion into your vein. You will receive your infusions in your doctor’s office, local clinic or hospital, or even your home. Talk to your doctor and insurance company about which location may be best and most affordable for you.

Entyvio infusions take about 30 minutes each time, but your entire clinic visit might take a couple of hours. You can usually go back to your normal activities after the infusion.

The cash price for Entyvio tends to run about $6,700 for a supply of one 300 mg vial of powder for injection. However, most patients do not pay this price or access the drug themselves; they receive it in the clinic. There may be additional costs for administration of the drug as well as the patient's time at the clinic.

If you have insurance, your copay for Entyvio will vary based on your formulary coverage or the type of government insurance you have. If you have private commercial insurance, you may be able to get Entyvio for as little as $5 per dose. If you do not have insurance, Takeda may still be able to offer you financial assistance.

Patients who receive governmental-sponsored insurance, such as Medicare, Medicaid, or TriCare are not eligible for the $5 copay program. However, you may still be able to get assistance through an independent copay foundation.

Takeda Pharmaceuticals offers a patient assistance program called EntyvioConnect that offers financial assistance, co-pay support, nurse resources and useful tips to help you manage your condition.

You can contact EntyvioConnect at 1-844-ENTYVIO (1-844-368-9846), Monday to Friday, from 8am to 8pm ET (except holidays).

How is Entyvio given?

Starting doses:

• You will be given 3 starting dose infusions of 30 minutes each. Initially, to start treatment, you will receive these infusions at week 0 (your 1st dose), week 2, and then at week 6.
• Most patients receive 300 mg per dose.

Maintenance doses:

• After your starting doses, you'll get one 30‑minute infusion every 8 weeks in order to keep your disease under control.
• After the first year, you will receive 6 Entyvio infusions per year.

Bottom Line

• Entyvio costs roughly $6,700 for a supply of one 300 mg vial of powder for injection. This drug is usually given in a doctor's office or clinic.
• However, most patients do not pay this price. Your price will vary based on your insurance type, formulary coverage and copay tier.
• If you don't have insurance or need other financial assistance, you can speak to a representative at Takeda Pharmaceuticals who can explain your options. Call 1-844-368-9846.

This is not all the information you need to know about Entyvio for safe and effective use. Review the full Entyvio product information here, and discuss this information with your doctor or other health care provider.