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Home > Medical Answers > What are the biosimilars of Herceptin?

What are the biosimilars of Herceptin?

Answers by TheMediTary.Com - Last updated: 13-Jul-2023

What are the biosimilars of Herceptin?

Herceptin (trastuzumab) is the original brand of trastuzumab, a biological medicine used to treat specific types of breast and gastric cancer, in specific patients and used in conjunction with prescribed treatment regimes.

What is the difference between generic and biosimilar medicines?

  • A biosimilar medicine is a copy of the original brand of biological medicine eg Ogivri is biosimilar of Herceptin.
  • A generic medicine is a copy of the original brand of small molecule drug eg Wal-Itin is a generic of Claritin.


The biosimilars of Herceptin are:

  • Herzuma
  • Kanjinti
  • Ogivri
  • Ontruzant
  • Trazimera

Table comparing Herceptin to its Biosimilars

Brand name Herceptin Herzuma Kanjinti Ogivri Ontruzant Trazimera
Active ingredient name trastuzumab trastuzumab-pkrb trastuzumab-anns trastuzumab-dkst trastuzumab-dttb trastuzumab-qyyp
Company Genentech Celltrion Allergan
Amgen
Mylan Samsung Bioepis Pfizer
Approval date (FDA) 25 September 1998 14 December 2018 13 June 2019 1 December 2017 18 January 2019 11March 2019
Interchangeable? No No No No No No
Treatment* Adjuvant breast cancer,
Metastatic breast cancer,
Metastatic gastric cancer
Adjuvant breast cancer,
Metastatic breast cancer,
Metastatic gastric cancer
Adjuvant breast cancer,
Metastatic breast cancer,
Metastatic gastric cancer
Adjuvant breast cancer,
Metastatic breast cancer,
Metastatic gastric cancer
Adjuvant breast cancer,
Metastatic breast cancer,
Metastatic gastric cancer
Adjuvant breast cancer,
Metastatic breast cancer,
Metastatic gastric cancer
Form 150mg Single use vial,
420mg Multiple use vial
150mg Single use vial,
420mg Multiple use vial
150mg Single use vial,
420mg Multiple use vial
150mg Single use vial,
420mg Multiple use vial
150mg Single use vial,
420mg Multiple use vial
150mg Single use vial,
420mg Multiple use vial
Administration route intravenous infusion intravenous infusion intravenous infusion intravenous infusion intravenous infusion intravenous infusion
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