Note: This document contains side effect information about capsaicin topical. Some dosage forms listed on this page may not apply to the brand name Menthac Arthritis Cream with Capsaicin.
Applies to capsaicin topical: topical cream, topical lotion, topical patch extended release, topical solution.
Serious side effects
Along with its needed effects, capsaicin topical (the active ingredient contained in Menthac Arthritis Cream with Capsaicin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking capsaicin topical:
More common - all forms
- Burning, itching, dryness, pain, redness, swelling, or soreness at the application site
Less common - all forms
- Body aches or pain
- chest tightness
- chills
- cough
- difficulty with breathing
- dry or productive cough
- ear congestion
- fever
- headache
- loss of voice
- sneezing
- sore throat
- stuffy or runny nose
- unusual tiredness or weakness
Less common - patch only
- Blurred vision
- breakdown of the skin
- dizziness
- nervousness
- pain in the arms or legs
- pounding in the ears
- slow or fast heartbeat
Incidence not known - patch only
- Bloating or swelling of the face, arms, hands, lower legs, or feet
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- eye irritation or pain
- increased sensitivity to pain or touch
- scarring of the skin
- stabbing pain
- throat irritation
- unusual weight gain or loss
Other side effects
Some side effects of capsaicin topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common - patch only
- Muscle aches
- nausea
- pain or tenderness around the eyes and cheekbones
- vomiting
Incidence not known - patch only
- Abnormal skin odor
- change in or loss of taste
For Healthcare Professionals
Applies to capsaicin topical: compounding powder, topical cream, topical film, topical gel, topical kit, topical liquid, topical lotion, topical stick.
General
The most commonly reported side effects were application site erythema and application site pain.[Ref]
Local
Very common (10% or more): Application site erythema (63%), application site pain (42%)
Common (1% to 10%): Application site pruritus, application site papules, application site edema, application site swelling, application site dryness
Uncommon (0.1% to 1%): Application site urticaria, application site paresthesia, application site dermatitis, application site hyperesthesia, application site excoriation, application site warmth, application site anesthesia, application site bruising, application site inflammation, application site exfoliation[Ref]
Cardiovascular
Common (1% to 10%): Hypertension
Uncommon (0.1% to 1%): First degree atrio-ventricular (AV) block, tachycardia, palpitations, increased blood pressure[Ref]
Dermatologic
Uncommon (0.1% to 1%): Herpes zoster, pruritus
Frequency not reported: Abnormal skin odor, second degree burns[Ref]
Respiratory
Common (1% to 10%): Nasopharyngitis, bronchitis, sinusitis
Uncommon (0.1% to 1%): Cough, throat irritation
Frequency not reported: Sneezing, dyspnea, wheezing, exacerbation of asthma, irritation of the mucous membranes of the respiratory tract (such as nasal and throat irritation)[Ref]
Gastrointestinal
Common (1% to 10%): Nausea[Ref]
Musculoskeletal
Uncommon (0.1% to 1%): Pain in extremity, muscle spasms[Ref]
Nervous system
Uncommon (0.1% to 1%): Dysgeusia, hypoesthesia, burning sensation
Frequency not reported: Headache, peripheral sensory neuropathy, dizziness, dysgeusia, hyperesthesia[Ref]
Ocular
Uncommon (0.1% to 1%): Eye irritation
Frequency not reported: Irritation of the mucous membranes of the eyes, runny eyes[Ref]
Other
Frequency not reported: Peripheral edema[Ref]
