Note: This document contains side effect information about mitomycin ophthalmic. Some dosage forms listed on this page may not apply to the brand name Mitosol.

Applies to mitomycin ophthalmic: ophthalmic powder for solution.

Serious side effects of Mitosol

Along with its needed effects, mitomycin ophthalmic (the active ingredient contained in Mitosol) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking mitomycin ophthalmic:

Incidence not known

• Blindness
• blurred vision
• decreased vision or any change in vision
• dislocated eye implants
• eye pain, redness, irritation, or inflammation
• flashes of light or floaters in vision
• headache
• red or bloodshot eye
• seeing flashes or sparks of light
• seeing floating spots before the eyes, or a veil or curtain appearing across part of vision
• tearing of the eyes

Other side effects of Mitosol

Some side effects of mitomycin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• Opening of the surgical wound
• raising of the upper eyelid
• sensitivity of the eyes to light
• throbbing pain

For Healthcare Professionals

Applies to mitomycin ophthalmic: ophthalmic kit.

General

The most commonly reported side effects include blebitis, corneal changes, and other localized reactions.^[Ref]

Ocular

Frequency not reported: Blebitis, bleb ulceration, chronic bleb leak, encapsulated/cystic bleb, bleb-related infection, conjunctival necrosis, thin-walled bleb, Descemet's detachment, induced astigmatism, corneal epithelial damage, superficial punctate keratitis, endophthalmitis, hypotony, choroidal reaction, choroidal detachment, choroidal reactions, choroidal detachment, choroidal effusion, serious choroidal detachment, suprachoroidal hemorrhage, hypotony maculopathy, presence of supraciliochoroidal effusion, iritis, cataract development, capsular constriction, posterior synechiae, retinal pigment epithelial tear, serous/rhegatogenous retinal detachment, hyphema, vitreal/retinal/subconjunctival/disk hemorrhage, macular edema, sclera thinning/ulceration, intraocular lens capture, disk swelling, malignant glaucoma, lacrimal drainage system obstruction, ciliary block, corneal vascularization, decreased visual acuity, cystic conjunctival degeneration, upper eyelid retraction, dislocated implants, severe loss of vision, hemiretinal/central retinal vein occlusion^[Ref]

Other

Frequency not reported: Wound dehiscence/scleral wound dehiscence^[Ref]

Cardiovascular

Frequency not reported: Blood clot^[Ref]