Note: This document contains side effect information about benzocaine topical. Some dosage forms listed on this page may not apply to the brand name Orabase.
Applies to benzocaine topical: cream, gel/jelly, lotion, lozenge/troche, ointment, paste, powder for suspension, solution, spray, swab. Other dosage forms:
- topical application cream, topical application gel/jelly, topical application liquid, topical application ointment, topical application solution, topical application spray
Serious side effects of Orabase
Along with its needed effects, benzocaine topical (the active ingredient contained in Orabase) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking benzocaine topical:
Incidence not known
- Bluish-colored lips, fingernails, or palms
- dark urine
- difficulty breathing
- dizziness or lightheadedness
- headache
- high fever
- nausea
- pale skin
- rapid heart rate
- sore throat
- unusual bleeding or bruising
- unusual tiredness or weakness
- vomiting
- worsening of pain, redness, swelling, or irritation in or around the mouth
For Healthcare Professionals
Applies to benzocaine topical: compounding powder, mucous membrane gel, mucous membrane liquid, mucous membrane lozenge, mucous membrane paste, mucous membrane powder for reconstitution, mucous membrane spray, mucous membrane swab, mucous membrane tablet disintegrating, rectal ointment, rectal suppository, topical cream, topical gel, topical liquid, topical lotion, topical ointment, topical spray, topical stick, topical swab.
Dermatologic
Dermatologic side effects have included contact dermatitis and urticaria.[Ref]
Local
Local side effects have included burning and stinging.[Ref]
Other
Other side effects have included edema.[Ref]
Cardiovascular
Cardiovascular side effects have included angioedema.
Hematologic
Hematologic side effects have included methemoglobinemia. FDA continues to receive reports of methemoglobinemia from postmarketing reporting.[Ref]
