Uses of Trazodone Tablets:

• It is used to treat low mood (depression).
• It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Trazodone Tablets?

• If you have an allergy to trazodone or any other part of this medicine (trazodone tablets).
• If you are allergic to this medicine (trazodone tablets); any part of this medicine (trazodone tablets); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
• If you have had a recent heart attack.
• If you have ever had a long QT on ECG or other heartbeat that is not normal.
• If you have any of these health problems: Low magnesium levels, low potassium levels, or slow heartbeat.
• If you are taking any of these drugs: Linezolid or methylene blue.
• If you have taken certain drugs for depression or Parkinson's disease in the last 14 days. This includes isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline. Very high blood pressure may happen.
• If you are taking any drugs that can cause a certain type of heartbeat that is not normal (prolonged QT interval). There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure.

This is not a list of all drugs or health problems that interact with this medicine (trazodone tablets).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (trazodone tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Trazodone Tablets?

• Tell all of your health care providers that you take this medicine (trazodone tablets). This includes your doctors, nurses, pharmacists, and dentists.
• Avoid driving and doing other tasks or actions that call for you to be alert until you see how this medicine (trazodone tablets) affects you.
• To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
• Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions.
• An unsafe heartbeat that is not normal (long QT on ECG) has happened with this medicine (trazodone tablets). This may raise the chance of sudden death. Talk with the doctor.
• This medicine may raise the chance of bleeding. Sometimes, bleeding can be life-threatening. Talk with the doctor.
• Some people may have a higher chance of eye problems with this medicine (trazodone tablets). Your doctor may want you to have an eye exam to see if you have a higher chance of these eye problems. Call your doctor right away if you have eye pain, change in eyesight, or swelling or redness in or around the eye.
• This medicine can cause low sodium levels. Very low sodium levels can be life-threatening, leading to seizures, passing out, trouble breathing, or death.
• If you are 65 or older, use this medicine (trazodone tablets) with care. You could have more side effects.
• Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

How is this medicine (Trazodone Tablets) best taken?

Use this medicine (trazodone tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Take this medicine (trazodone tablets) right after a meal or light snack.
• Tablet may be broken in half.
• Do not chew or crush.
• If you feel sleepy after taking this medicine (trazodone tablets), talk with your doctor. Your doctor may change your dose or when you take this medicine (trazodone tablets).
• Keep taking this medicine (trazodone tablets) as you have been told by your doctor or other health care provider, even if you feel well.
• It may take several weeks to see the full effects.
• Do not stop taking this medicine (trazodone tablets) all of a sudden without calling your doctor. You may have a greater risk of side effects. If you need to stop this medicine (trazodone tablets), you will want to slowly stop it as ordered by your doctor.

What do I do if I miss a dose?

• Take a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not take 2 doses at the same time or extra doses.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of low sodium levels like headache, trouble focusing, memory problems, feeling confused, weakness, seizures, or change in balance.
• Signs of bleeding like throwing up or coughing up blood; vomit that looks like coffee grounds; blood in the urine; black, red, or tarry stools; bleeding from the gums; abnormal vaginal bleeding; bruises without a cause or that get bigger; or bleeding you cannot stop.
• Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
• Fast or abnormal heartbeat.
• Swelling.
• Feeling confused.
• Call your doctor right away if you have a painful erection (hard penis) or an erection that lasts for longer than 4 hours. This may happen even when you are not having sex. If this is not treated right away, it may lead to lasting sex problems and you may not be able to have sex.
• A severe and sometimes deadly problem called serotonin syndrome may happen. The risk may be greater if you also take certain other drugs. Call your doctor right away if you have agitation; change in balance; confusion; hallucinations; fever; fast or abnormal heartbeat; flushing; muscle twitching or stiffness; seizures; shivering or shaking; sweating a lot; severe diarrhea, upset stomach, or throwing up; or very bad headache.

What are some other side effects of Trazodone Tablets?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Feeling dizzy, sleepy, tired, or weak.
• Diarrhea or constipation.
• Dry mouth.
• Stomach pain.
• Headache.
• Upset stomach or throwing up.
• Feeling nervous and excitable.
• Shakiness.
• Muscle pain.
• Stuffy nose.
• Weight gain or loss.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Trazodone Tablets?

• Store at room temperature.
• Protect from light.
• Store in a dry place. Do not store in a bathroom.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer Information Use and Disclaimer

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this medicine (trazodone tablets) is refilled. If you have any questions about this medicine (trazodone tablets), please talk with the doctor, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Frequently asked questions

• Does trazodone cause weight gain?
• Will trazodone help me sleep?
• Does Seroquel help you sleep?
• How long does trazodone stay in your system?
• How long does it take for trazodone to work?
• Is trazodone a controlled substance?
• Can trazodone be given to dogs?

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