Ciprodex ear drops Pregnancy Warnings
Animal reproduction studies of ciprofloxacin have revealed evidence of abortion at doses that produced maternal gastrointestinal disturbances and weight loss. Corticosteroids have revealed evidence of teratogenicity and changes to the testes, epididymis, sperm duct, prostate, seminal vesicle, Cowper's and accessory glands after dermal administration. There are no controlled data for either drug in human pregnancy.
US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus.
US FDA pregnancy category: C
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Ciprodex ear drops Breastfeeding Warnings
Use is not recommended and a decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.
Excreted into human milk: Unknown
Excreted into animal milk: Unknown
Comment: The effects in the nursing infant are unknown.
Ciprofloxacin and corticosteroids, such as dexamethasone, are excreted into breastmilk when administered orally. Excreted dexamethasone may result in growth suppression, interference with endogenous corticosteroid production, and/or other effects in the infant.
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