Summary

Commonly reported side effects of rosuvastatin include: myalgia. Other side effects include: asthenia. Continue reading for a comprehensive list of adverse effects.

Applies to rosuvastatin: oral capsules, oral tablets.

Side effects include:

Headache, nausea, myalgia, asthenia, constipation, abdominal pain.

For Healthcare Professionals

Applies to rosuvastatin: oral capsule, oral tablet.

General

The most frequently reported side effects included headache, myalgia, abdominal pain, asthenia, and nausea.^[Ref]

Musculoskeletal

Very common (10% or more): Myalgia (up to 12.7%), arthralgia (10.1%)

Rare (less than 0.1%): Myopathy, rhabdomyolysis, myositis

Frequency not reported: Immune-mediated necrotizing myopathy, tendon disorders, creatine phosphokinase increased^[Ref]

Gastrointestinal

Common (1% to 10%): Abdominal pain, nausea, constipation

Rare (less than 0.1%): Pancreatitis

Frequency not reported: Diarrhea^[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness

Very rare (less than 0.01%): Polyneuropathy, memory loss

Postmarketing reports: Cognitive impairment, forgetfulness, amnesia, memory impairment, peripheral neuropathy^[Ref]

Hepatic

Rare (0.01% to 0.1%): Hepatic transaminases/enzymes increased

Very rare (less than 0.01%): Jaundice, hepatitis

Frequency not reported: Bilirubin increased

Postmarketing reports: Fatal hepatic failure, nonfatal hepatic failure^[Ref]

Dermatologic

Uncommon (0.1% to 1%): Rash, pruritus, urticaria

Rare (less than 0.1%): Angioedema

Frequency not reported: Stevens-Johnson syndrome^[Ref]

Renal

Frequency not reported: Acute renal failure^[Ref]

Genitourinary

Very rare (less than 0.01%): Hematuria

Frequency not reported: Proteinuria, myoglobinuria, sexual dysfunction^[Ref]

Other

Common (1% to 10%): Asthenia

Frequency not reported: Edema, glutamyl transpeptidase increased, alkaline phosphatase increased^[Ref]

Respiratory

Frequency not reported: Cough, dyspnea, interstitial lung disease^[Ref]

Psychiatric

Frequency not reported: Confusion, depression, insomnia, nightmares, sleep disorders/disturbances^[Ref]

Endocrine

Very rare (less than 0.01%): Gynecomastia

Frequency not reported: Thyroid function abnormalities^[Ref]

Metabolic

Common (1% to 10%): Diabetes mellitus

Frequency not reported: Glucose elevated, HbA1c increased^[Ref]

Hematologic

Rare (less than 0.1%): Thrombocytopenia^[Ref]

Hypersensitivity

Rare (less than 0.1%): Hypersensitivity reaction^[Ref]