Applies to phenylephrine/pyrilamine: oral liquid, oral suspension, oral suspension extended release, oral tablet, oral tablet chewable, oral tablet chewable extended release.

Cardiovascular

Cardiovascular side effects have included hypotension, hypertension, cardiac arrhythmias and palpitations.^[Ref]

Dermatologic

Dermatologic side effects have included urticaria, drug rash, photosensitivity and pruritus.^[Ref]

Gastrointestinal

Gastrointestinal side effects have included epigastric discomfort, anorexia, vomiting, diarrhea, and constipation.^[Ref]

Genitourinary

Genitourinary side effects have included urinary frequency and difficult urination.^[Ref]

Nervous system

Nervous system side effects have included drowsiness, sedation, disturbed coordination, tremor, irritability, insomnia, nervousness, convulsions, headache, euphoria, and dysphoria.^[Ref]

Ocular

Ocular side effects have included visual disturbances.^[Ref]

Hematologic

Hematologic side effects have included hemolytic anemia, thrombocytopenia, and agranulocytosis.^[Ref]

Respiratory

Respiratory side effects have included tightness of chest, wheezing, and shortness of breath.^[Ref]

General

General side effects have included dryness of mucous membranes.^[Ref]