Applies to teprotumumab: intravenous powder for solution.
Serious side effects of Teprotumumab
Along with its needed effects, teprotumumab may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking teprotumumab:
More common
- Blurred vision
- dry mouth
- flushed, dry skin
- fruit-like breath odor
- increased hunger
- increased thirst
- increased urination
- nausea
- stomach pain
- sweating
- trouble breathing
- unexplained weight loss
- unusual tiredness or weakness
- vomiting
Less common
- Fast, pounding, or irregular heartbeat or pulse
- feeling hot
- headache
- muscle pain
Incidence not known
- Bleeding from the rectum
- diarrhea that may contain blood
- severe stomach pain
Other side effects of Teprotumumab
Some side effects of teprotumumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Change or loss of hearing
- change or loss of taste
- dry skin
- hair loss or thinning of the hair
- mild diarrhea
- muscle spasms
- unusual tiredness or weakness
Incidence not known
- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
For Healthcare Professionals
Applies to teprotumumab: intravenous powder for injection.
Musculoskeletal
Very common (10% or more): Muscle spasms (25%)[Ref]
Gastrointestinal
Very common (10% or more): Nausea (17%), diarrhea (12%)
Common (1% to 10%): Dysgeusia
Frequency not reported: Exacerbation of inflammatory bowel disease[Ref]
Metabolic
Very common (10% or more): Hyperglycemia (10%)[Ref]
Nervous system
Common (1% to 10%): Headache[Ref]
Dermatologic
Very common (10% or more): Alopecia (13%)
Common (1% to 10%): Dry skin[Ref]
Other
Very common (10% or more): Fatigue (12%), hearing impairment (10%)
Common (1% to 10%): Infusion reactions (transient blood pressure increases, feeling hot, tachycardia, dyspnea, headache, and muscle pain)[Ref]
