Applies to thyroid desiccated: oral tablets.

Side effects include:

Adverse reactions result from overdosage and resemble manifestations of hyperthyroidism, including fatigue, weight loss, increased appetite, heat intolerance, fever, excessive sweating, headache, hyperactivity, nervousness, anxiety, irritability, emotional lability, insomnia, tremor, muscle weakness, palpitations, tachycardia, arrhythmias, increased heart rate and BP, heart failure, angina, AMI, cardiac arrest, diarrhea, vomiting, abdominal cramps, elevations in liver function tests, hair loss, flushing, decreased bone mineral density, menstrual irregularities, and impaired fertility.

For Healthcare Professionals

Applies to thyroid desiccated: compounding powder, oral capsule, oral tablet.

General

Adverse reactions other than those attributable to hyperthyroidism due to therapeutic overdose are rare. Excessive doses may result in a hypermetabolic state resembling in every respect the condition of endogenous origin.^[Ref]

If sings and symptoms of overdosage appear, the dosage should be reduced or therapy temporarily discontinued and may be reinstituted at a lower dosage. Normal hypothalamic-pituitary-thyroid axis function has been restored in 6 to 8 weeks after thyroid suppression.^[Ref]