Note: This document contains side effect information about desoximetasone topical. Some dosage forms listed on this page may not apply to the brand name Topicort.
Applies to desoximetasone topical: topical application cream, topical application gel/jelly, topical application ointment, topical application spray.
Serious side effects of Topicort
Along with its needed effects, desoximetasone topical (the active ingredient contained in Topicort) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking desoximetasone topical:
Rare
- Flushing or redness of the skin
- redness, blistering, peeling, or loosening of the skin
- unusually warm skin
Incidence not known
- Blindness
- blistering, burning, crusting, dryness, or flaking of the skin
- blurred vision
- decreased vision
- eye pain
- headache
- irritation
- itching, scaling, severe redness, soreness, or swelling of the skin
- nausea or vomiting
- redness and scaling around the mouth
- tearing
- thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (eg, between the fingers)
- thinning, weakness, or wasting away of the skin
Other side effects of Topicort
Some side effects of desoximetasone topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Rare
- Burning, itching, and pain in hairy areas, or pus at the root of the hair
Incidence not known
- Acne or pimples
- burning and itching of the skin with pinhead-sized red blisters
- increased hair growth on the forehead, back, arms, and legs
- lightening of normal skin color
- lightening of treated areas of dark skin
- reddish purple lines on the arms, face, legs, trunk, or groin
- softening of the skin
For Healthcare Professionals
Applies to desoximetasone topical: compounding powder, topical cream, topical gel, topical ointment, topical spray.
General
The most commonly reported side effects were application site dryness, application site irritation, and application site pruritus.[Ref]
Endocrine
Frequency not reported: Hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome[Ref]
Dermatologic
Frequency not reported: Folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, miliaria[Ref]
Local
Common (1% to 10%): Application site dryness, application site irritation, application site pruritus
Frequency not reported: Burning, itching[Ref]
Metabolic
Frequency not reported: Hyperglycemia, latent diabetes mellitus[Ref]
