Applies to travoprost ophthalmic: ophthalmic solution.

Serious side effects

Along with its needed effects, travoprost ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking travoprost ophthalmic:

More common

• Eye pain
• itching eye
• redness of the eye
• redness, swelling, or itching of eyelid

Less common

• Blurred or decreased vision
• burning, dry, or itching eyes
• eye color changes
• redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid

Other side effects

Some side effects of travoprost ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Eye discomfort
• feeling of having something in the eye

Less common

• Acid or sour stomach (heartburn or indigestion)
• blood in the urine
• chest pain or tightness
• dry eyes
• eye discharge or excessive tearing
• faintness or lightheadedness when getting up from a lying or sitting position
• loss of bladder control
• lower back pain
• muscle pain or stiffness
• pain, swelling, or redness in the joints
• pain or burning while urinating
• pelvic pain
• slow or irregular heartbeat (less than 50 beats per minute)

For Healthcare Professionals

Applies to travoprost ophthalmic: ophthalmic solution.

Ocular

Very common (10% or more): Ocular hyperemia (up to 50%)

Common (1% to 10%): Decreased visual acuity, eye discomfort, foreign body sensation, eye pain, eyelid pruritus, abnormal vision, blepharitis, blurred vision, cataract, conjunctivitis, corneal staining, dry eye, iris discoloration, keratitis, lid margin crusting, ocular inflammation, photophobia, subconjunctival hemorrhage, tearing

Uncommon (0.1% to 1%): Corneal erosion, uveitis, iritis, anterior chamber inflammation, punctate keratitis, eye discharge, erythema of eyelid, periorbital edema, ectropion cataract, eyelid margin crusting, growth of eyelashes, eyelash discoloration, asthenopia

Rare (less than 0.1%): Iridocyclitis, eye inflammation, photopsia, eyelid eczema, conjunctival edema, halo vision, conjunctival follicles, eye hypoesthesia, meibomianitis, anterior chamber pigmentation, mydriasis, eyelash thickening, macular edema, sunken eyes

Postmarketing reports: Periorbital/lid changes (including deepening of the eyelid sulcus)^[Ref]

Dermatologic

Uncommon (0.1% to 1%): Skin hyperpigmentation (periocular), skin discoloration, abnormal hair texture, hypertrichosis

Rare (less than 0.1%): Allergic dermatitis, contact dermatitis, erythema, rash, hair color changes, madarosis

Frequency not reported: Pruritus, abnormal hair growth^[Ref]

Cardiovascular

Common (1% to 10%): Angina pectoris, bradycardia, chest pain, hypertension, hypotension

Uncommon (0.1% to 1%): Palpitations

Rare (less than 0.1%): Irregular heart rate, decreased heart rate, decreased diastolic blood pressure, increased systolic blood pressure

Frequency not reported: Tachycardia

Postmarketing reports: Arrhythmia^[Ref]

Gastrointestinal

Common (1% to 10%): Dyspepsia, gastrointestinal disorder

Rare (less than 0.1%): Reactivated peptic ulcer, constipation, dry mouth

Frequency not reported: Diarrhea, abdominal pain, nausea

Postmarketing reports: Vomiting^[Ref]

Genitourinary

Common (1% to 10%): Prostate disorder, urinary incontinence, urinary tract infections

Frequency not reported: Dysuria, increased prostatic specific antigen^[Ref]

Musculoskeletal

Common (1% to 10%): Arthritis, back pain

Uncommon (0.1% to 1%): Shoulder pain

Rare (less than 0.1%): Musculoskeletal pain

Frequency not reported: Arthralgia^[Ref]

Nervous system

Common (1% to 10%): Headache

Uncommon (0.1% to 1%): Dizziness

Rare (less than 0.1%): Dysgeusia

Frequency not reported: Vertigo, tinnitus^[Ref]

Respiratory

Common (1% to 10%): Bronchitis, cold/flu syndrome, sinusitis

Uncommon (0.1% to 1%): Dyspnea, asthma, nasal congestion, throat irritation

Rare (less than 0.1%): Respiratory disorder, oropharyngeal pain, cough, dysphonia

Frequency not reported: Aggravated asthma

Postmarketing reports: Epistaxis^[Ref]

Metabolic

Common (1% to 10%): Hypercholesterolemia^[Ref]

Other

Common (1% to 10%): Pain

Uncommon (0.1% to 1%): Asthenia, malaise^[Ref]

Psychiatric

Common (1% to 10%): Anxiety, depression

Postmarketing reports: Insomnia^[Ref]

Immunologic

Rare (less than 0.1%): Herpes simplex, herpetic keratitis^[Ref]

General

The most commonly reported side effect was ocular hyperemia.^[Ref]

Hypersensitivity

Uncommon (0.1% to 1%): Hypersensitivity, seasonal allergy^[Ref]