Methotrexate overdosage occurs when too high a dose is administered to a patient. Toxic effects may be experienced hours, days or even weeks after exposure and include may include pale skin, easy bruising or bleeding, unusual weakness, mouth sores, nausea, vomiting, black or bloody stools, coughing up blood or vomit that looks like coffee grounds, and urinating less than usual or not at all.
Drugs used to treat Methotrexate Overdosage
| Name | Drug Class |
|---|---|
| Levoleucovorin | Antidotes |
| Leucovorin (injection) | Antidotes |
| Leucovorin | Antidotes |
| Glucarpidase | Antidotes |
| Voraxaze | Antidotes |
