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Home > Drugs > Treatments > Pruritus

Medications for Pruritus

Other names: Itching; Itchy Skin

Pruritus is another name for itchy skin. Symptoms vary depending on the cause but may include:

  • Generalized itchy skin all over the body or an itch localized to just one or a few small areas
  • Patches of red, bumpy, or irritated looking skin
  • Leathery or scaly skin
  • Cracked skin
  • Areas of broken or bleeding skin where you have scratched
  • Isolated crusty patches of skin that weep or have pus from a bacterial infection
  • Dry skin in other areas.

For some people, it can be hard not to itch. Unfortunately, this makes the skin itchier and it can be difficult to break this itch-scratch cycle once it has started.

What Causes Pruritus?

Pruritus is more common as people age, because skin tends to become drier. Causes of pruritus include:

  • Burns
  • Dermatitis (eczema)
  • Dry skin
  • Hives
  • Insect bites
  • Nerve conditions, such as diabetes, multiple sclerosis, pinched nerves, or shingles
  • Pregnancy
  • Psoriasis
  • Psychiatric conditions, such as anxiety, depression, obsessive-compulsive disorder
  • Scabies
  • Scars
  • Underlying medical conditions (such as cancer, iron deficiency anemia, kidney failure, liver disease, or thyroid disease).

Sometimes doctors cannot find an underlying reason for the pruritus.

How is Pruritus Treated?

Treatment varies depending on the cause.

If dry skin is an underlying cause, then daily moisturizing is important, as is only using gentle cleansers and bathing in lukewarm water (hot water can dry out skin even more). Common treatments that may be used include:

  • Moisturizers
  • Anti-itch shower/bath products
  • Oral antihistamines
  • Oral SSRI antidepressants can also help relieve itch
  • Corticosteroid creams/ointments/lotions
  • Other creams/ointments (eg, calcineurin inhibitors, topical anesthetics, capsaicin)
  • Moist dressings
  • Phototherapy (light therapy).

See your doctor or a dermatologist (skin disease specialist) if your pruritus affects your whole body or has lasted more than two weeks and is not getting better with self-help measures. Also make an appointment if the itching is accompanied by other symptoms such as weight loss, fatigue, fever, or changes in bowel habits.

Drugs used to treat Pruritus

Name Drug Class Updated
Ammonium lactate topical Topical emollients 16-Aug-2023
Amlactin ultra Topical emollients 16-Aug-2023
Amlactin foot cream therapy Topical emollients 16-Aug-2023
Amlactin cerapeutic Topical emollients 16-Aug-2023
Crotamiton topical Topical anti-infectives 15-Aug-2023
Calamine (topical) Miscellaneous topical agents 15-Aug-2023
Proctosol-hc (cream, suppository) Topical steroids 15-Aug-2023
Lac-hydrin 5 Topical emollients 14-Aug-2023
Menthol topical (oral mucous membrane) Topical rubefacient 13-Aug-2023
Menthol topical Topical rubefacient 13-Aug-2023
Hydrocortisone and lidocaine (topical/rectal) Topical anesthetics 13-Aug-2023
Vapodrops menthol (oral mucous membrane) Topical rubefacient 12-Aug-2023
Doxepin topical Topical antihistamines 12-Aug-2023
Pramoxine topical Topical anesthetics 12-Aug-2023
Pramoxine (monograph) Drugs 12-Aug-2023
Aquaphor itch relief maximum strength Topical steroids 08-Aug-2023
Aquaphor itch relief Topical steroids 08-Aug-2023
Proctosol-hc Topical steroids 07-Aug-2023
Proctocort Topical steroids 07-Aug-2023
Anusol-hc Topical steroids 07-Aug-2023
Procto-pak 1% Topical steroids 07-Aug-2023
Procto-med hc Topical steroids 07-Aug-2023
Ala-scalp Topical steroids 07-Aug-2023
Preparation h hydrocortisone Topical steroids 07-Aug-2023
Locoid lotion Topical steroids 07-Aug-2023
Locoid lipocream Topical steroids 07-Aug-2023
Prudoxin Topical antihistamines 06-Aug-2023
Anusol-hc (cream, suppository) Topical steroids 05-Aug-2023
Anucort-hc (cream, suppository) Topical steroids 05-Aug-2023
Lanacane Topical anesthetics 05-Aug-2023
Amlactin Topical emollients 05-Aug-2023
Kerasal al Topical emollients 05-Aug-2023
Proctozone hc (cream, suppository) Topical steroids 05-Aug-2023
Laclotion Topical emollients 05-Aug-2023
Lac-hydrin Topical emollients 05-Aug-2023
Proctocort (cream, suppository) Topical steroids 05-Aug-2023
Ana-lex (topical/rectal) Drugs 04-Aug-2023
Zonalon Topical antihistamines 14-Jul-2023
Vanamine pd Drugs 14-Jul-2023
Scot-tussin allergy relief formula Anticholinergic antiemetics 14-Jul-2023
Regenecare ha spray Topical anesthetics 14-Jul-2023
Medi-quik spray Topical anesthetics 13-Jul-2023
Locoid Topical steroids 13-Jul-2023
Gold bond anti-itch lotion Topical anesthetics 13-Jul-2023
Geri-hydrolac Topical emollients 13-Jul-2023
Eurax Topical anti-infectives 13-Jul-2023
Dermoplast Topical anesthetics 13-Jul-2023
Calamine plain (topical) Miscellaneous topical agents 13-Jul-2023
Bactine Topical anesthetics 12-Jul-2023
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