Note: This document contains side effect information about faricimab. Some dosage forms listed on this page may not apply to the brand name Vabysmo.
Applies to faricimab: intraocular solution.
Serious side effects of Vabysmo
Along with its needed effects, faricimab (the active ingredient contained in Vabysmo) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking faricimab:
More common
- Bloody eye
- redness of the eye
Less common
- Blurred vision
- change in vision
- eye pain
- loss of vision
- red, sore eyes
- seeing floaters, veil or curtain appearing across part of vision
- seeing floating dark spots or material before the eyes
- tearing
Rare
- Eye irritation
- seeing light flashes
- watering of the eyes
Incidence not known
- Chest pain, discomfort, or tightness
- fast heartbeat
- fever
- hives, itching, rash
- hoarseness
- irritation
- joint pain, stiffness, or swelling
- nausea
- pain or discomfort in the arms, jaw, back, or neck
- redness of the skin
- stroke
- sweating
- swelling of the eyelids, face, lips, hands, or feet
- trouble breathing
- vomiting
For Healthcare Professionals
Applies to faricimab: intravitreal solution.
Cardiovascular
In the neovascular age-related macular degeneration studies, arterial thromboembolic events were reported in 1% of patients during the first year. In the diabetic macular edema studies, arterial thromboembolic events were reported in 2% of patients during the first year.[Ref]
Common (1% to 10%): Arterial thromboembolic events (defined as nonfatal stroke, nonfatal myocardial infarction, vascular death [including deaths of unknown cause])[Ref]
Hypersensitivity
Frequency not reported: Hypersensitivity reactions[Ref]
Immunologic
Very common (10% or more): Anti-drug antibodies (up to 10.4%)[Ref]
Ocular
Very common (10% or more): Cataract (10.7%)
Common (1% to 10%): Conjunctival hemorrhage, eye pain, increased intraocular pressure, increased lacrimation, retinal pigment epithelial tear, vitreous floaters
Uncommon (0.1% to 1%): Blurred vision, corneal abrasion, conjunctival hyperemia, endophthalmitis, eye irritation, eye pruritus, iridocyclitis, iritis, ocular discomfort, ocular hyperemia, retinal tear, sensation of foreign body, uveitis, reduced visual acuity, vitreous hemorrhage, vitritis
Rare (0.01% to 0.1%): Rhegmatogenous retinal detachment, transiently reduced visual acuity[Ref]
