Note: This document contains side effect information about tioconazole topical. Some dosage forms listed on this page may not apply to the brand name Vagistat-1.

Applies to tioconazole topical: intravaginal ointment.

Side effects include:

Vulvovaginal burning, irritation, vaginitis, pruritus, headache.

For Healthcare Professionals

Applies to tioconazole topical: vaginal ointment w/applicator.

Other

Topical solution:

-Common (1% to 10%): Peripheral edema

-Frequency not reported: Pain^[Ref]

Dermatologic

Topical solution:

-Uncommon (0.1% to 1%): Rash, dermatitis

-Frequency not reported: Bullous eruption, contact dermatitis, dry skin, nail disorder (including nail discoloration, periungual inflammation, nail pain), pruritus, skin irritation, skin exfoliation, urticaria^[Ref]

Local

Topical solution: Local irritation (including local allergic reactions) usually occurred during the first week of therapy and was transient and mild.^[Ref]

Topical solution:

-Frequency not reported: Local irritation (including local allergic reactions)

Vaginal ointment:

-Frequency not reported: Burning, itching, pain, irritation, dryness^[Ref]

Genitourinary

Vaginal ointment:

-Frequency not reported: Increased vaginal burning, increased vaginal itching, increased vaginal irritation, vaginal swelling/redness, difficulty/burning on urination^[Ref]

Gastrointestinal

Vaginal ointment:

-Frequency not reported: Abdominal pain/cramping^[Ref]

Hypersensitivity

Topical solution:

-Frequency not reported: Allergic reaction

Other formulations than the dermatological preparation:

-Frequency not reported: Anaphylactoid reactions^[Ref]

Nervous system

Topical solution:

-Frequency not reported: Paresthesia

Vaginal ointment:

-Frequency not reported: Headache^[Ref]

Ocular

Topical solution:

-Frequency not reported: Periorbital edema^[Ref]

Respiratory

Vaginal ointment:

-Frequency not reported: Upper respiratory infection^[Ref]