Note: This document contains side effect information about lifitegrast ophthalmic. Some dosage forms listed on this page may not apply to the brand name Xiidra.
Applies to lifitegrast ophthalmic: ophthalmic solution.
Serious side effects of Xiidra
Along with its needed effects, lifitegrast ophthalmic (the active ingredient contained in Xiidra) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking lifitegrast ophthalmic:
More common
- Changes in vision
- eye irritation or discomfort
Less common
- Blurred vision
- redness of the white part of the eyes or inside of the eyelids
Other side effects of Xiidra
Some side effects of lifitegrast ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Change in taste
- loss of taste
Less common
- Cough
- discomfort or itching of the eyes
- drainage from the eyes
- fever
- headache
- pain or tenderness around the eyes and cheekbones
- stuffy or runny nose
- tightness of the chest
- troubled breathing
- watering of the eyes
For Healthcare Professionals
Applies to lifitegrast ophthalmic: ophthalmic solution.
General
The most commonly reported side effects included instillation site irritation, dysgeusia, reduced visual acuity, and eye pain.[Ref]
Ocular
Very common (10% or more): Reduced visual acuity (up to 25%), eye irritation (up to 18%), eye pain (up to 12%)
Common (1% to 10%): Conjunctival hyperemia, eye discharge, eye discomfort, eye pruritus, increased lacrimation[Ref]
Local
Very common (10% or more): Instillation site irritation (up to 25%), instillation site reactions (up to 12%)
Frequency not reported: Instillation site lacrimation, instillation site pain, instillation site pruritus[Ref]
Nervous system
Very common (10% or more): Dysgeusia (up to 25%)
Common (1% to 10%): Blurred vision, headache
Frequency not reported: Tension headache[Ref]
Respiratory
Common (1% to 10%): Sinusitis
Postmarketing reports: Bronchospasm, dyspnea, respiratory distress[Ref]
Hypersensitivity
Frequency not reported: Hypersensitivity
Postmarketing reports: Anaphylactic reaction, angioedema[Ref]
Immunologic
Postmarketing reports: Allergic conjunctivitis, allergic dermatitis, asthma, pharyngeal edema, type IV hypersensitivity reaction[Ref]
Gastrointestinal
Postmarketing reports: Swollen tongue[Ref]
