Note: This document contains side effect information about zinc sulfate. Some dosage forms listed on this page may not apply to the brand name Zinc-220.

Applies to zinc sulfate: oral capsule, oral tablet, oral tablet extended release. Other dosage forms:

• intravenous solution

Serious side effects of Zinc-220

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

Other side effects of Zinc-220

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to zinc sulfate: compounding powder, intravenous solution, oral capsule, oral tablet.

Gastrointestinal

Gastrointestinal side effects of zinc sulfate (the active ingredient contained in Zinc-220) when taken in large doses have included diarrhea, abdominal cramps, and vomiting, usually within 3 to 10 hours of dosing. The symptoms go away soon after discontinuation.^[Ref]

Respiratory

Respiratory side effects have included losing sense of smell in patients who use nasal sprays containing zinc.^[Ref]