Summary
Commonly reported side effects of betamethasone/clotrimazole topical include: adrenal suppression. Continue reading for a comprehensive list of adverse effects.
Applies to betamethasone/clotrimazole topical: topical cream, topical lotion.
Serious side effects
Along with its needed effects, betamethasone/clotrimazole topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking betamethasone / clotrimazole topical:
Less common
- Blistering, burning, itching, peeling, dryness, redness, or other signs of skin irritation not present before use of this medicine
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- hives
Rare
- Chills
- cough
- fever
- hoarseness
- lower back or side pain
- painful or difficult urination
- rash
- stinging
- swelling
Incidence not known
- Blindness
- blurred vision
- change in vision
- decreased vision
- dry mouth
- eye pain
- full or round face, neck, or trunk
- headache
- irritability
- nausea
- reddish purple lines on the arms, face, legs, trunk, or groin
- redness and scaling around the mouth
- softening of the skin
- stomach pain
- tearing
- unusual tiredness or weakness
- vomiting
For Healthcare Professionals
Applies to betamethasone / clotrimazole topical: topical cream, topical lotion.
General
The most frequently reported side effects are rash, edema, paresthesia, and secondary infections.[Ref]
Local
Topical corticosteroids:
-Frequency not reported: Burning, itching, irritation, dryness, folliculitis, blistering, peeling, redness, swelling, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, miliaria, irritation, telangiectasia, sensitization[Ref]
Endocrine
Frequency not reported: Hypothalamic-pituitary adrenal (HPA) axis suppression, Cushing's syndrome[Ref]
Nervous system
Common (1% to 10%): Paresthesia
Frequency not reported: Intracranial hypertension[Ref]
Musculoskeletal
Frequency not reported: Growth retardation[Ref]
Dermatologic
Frequency not reported: Rash, maculopapular rash
Betamethasone dipropionate:
-Frequency not reported: Burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hyperpigmentation, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, skin atrophy, striae miliaria, ecchymoses, telangiectasia
Clotrimazole:
-Frequency not reported: Erythema, stinging, blistering, peeling, pruritus, urticaria, general irritation[Ref]
Immunologic
Betamethasone dipropionate:
-Frequency not reported: Sensitization[Ref]
Genitourinary
Topical corticosteroids:
-Frequency not reported: Glucosuria[Ref]
Ocular
Betamethasone dipropionate:
-Frequency not reported: Blurred vision[Ref]
Metabolic
Topical corticosteroids:
-Frequency not reported: Hyperglycemia[Ref]
Other
Frequency not reported: Edema, secondary infection
Betamethasone dipropionate:
-Frequency not reported: Secondary infection
Clotrimazole:
-Frequency not reported: Edema[Ref]
