By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo

TheMediTary.Com

Medical Information, Documents, News - TheMediTary.Com

  • Home
  • News
  • Drugs
  • Drugs A-Z
  • Medical Answers
  • About Us
  • Contact
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo
Search Drugs
  • Drugs
    • Latest Drugs
    • Drugs A-Z
    • Medical Answers
  • News
    • FDA Alerts
    • Medical News
    • Health
    • Consumer Updates
    • Children's Health
  • More TheMediTary.Com
    • About Us
    • Contact
Follow US
Home > Drugs > Miscellaneous anxiolytics, sedatives and hypnotics > Daridorexant > Daridorexant Dosage
Miscellaneous anxiolytics, sedatives and hypnotics
https://themeditary.com/dosage-information/daridorexant-dosage-9092.html

Daridorexant Dosage

Drug Detail:Daridorexant (Daridorexant [ dar-i-doe-rex-ant ])

Drug Class: Miscellaneous anxiolytics, sedatives and hypnotics

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

Usual Adult Dose for Insomnia

Recommended dose: 25 to 50 mg once per night, orally
Maximum dose: 50 mg

Comments:

  • Take no more than once per night within 30 minutes of going to bed, and with at least 7 hours remaining prior to awakening.
  • The failure of insomnia to remit after 7 to 10 days of treatment may indicate the presence of a primary psychiatric or medical illness that should be evaluated.

Use: Treatment of adults with insomnia

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

  • Mild liver dysfunction: No adjustment recommended.
  • Moderate liver dysfunction (Child-Pugh score 7 to 9): Maximum recommended dose of 25 mg no more than once per night.
  • Severe liver dysfunction: Not recommended.

Dose Adjustments

Co-administration with Moderate CYP450 3A4 inhibitors:

  • Recommended dose: 25 mg no more than once per night

Co-administration with Strong CYP450 3A4 inhibitors: Avoid use
Co-administration with Strong or Moderate CYP450 3A4 inducers: Avoid use

Liver Dysfunction:
  • Moderate liver dysfunction (Child-Pugh score 7 to 9): Maximum recommended dose of 25 mg no more than once per night.
  • Severe liver dysfunction (Child-Pugh score equal or greater than 10): Not recommended.

Precautions

CONTRAINDICATIONS:

  • Patients with narcolepsy

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

US Controlled Substance: Schedule to be determine after review by the Drug Enforcement Administration.

Dialysis

Data not available

Other Comments

Administration advice:

  • Initiate treatment only after careful evaluation of the patient. Failure to respond after 7 to 10 days of treatment may indicate the presence of a primary psychiatric or medical illness that should be evaluated.
  • Should be taken orally no more than once per night within 30 minutes of going to bed.
  • Should be taken with at least 7 hours of sleep remaining prior to planned awakening.
  • Can be taken with or without food, however time to sleep onset may be delayed if taken with or soon after a meal.
  • Advise patients about the potential for next-day somnolence. Caution against driving and doing other activities that require complete mental alertness.
  • Particular caution is advised with elderly patients that are at higher risk of falls.
  • Advise not to consume alcohol or take with other CNS depressants.

Storage requirements:
  • Store at 20C to 25C (68F to 77F), excursions permitted between 15C and 30C (59F and 86F)

Monitoring:
  • In patients with psychiatric disorders monitor new or worsening depression or appearance of suicidal thoughts.
  • Monitor appearance of complex sleep behaviors such as sleepwalking, sleep driving or engaging in other activities while sleeping. Discontinue immediately if a patient experiences a complex sleep behavior.
  • Monitor respiratory function in patients with obstructive sleep apnea or chronic obstructive pulmonary disease.

Patient advice:
  • Read the US FDA-approved patient labeling (Patient Information and Instructions for Use).
  • Take orally no more than once per night within 30 minutes of going to bed and with at least 7 hours of sleep remaining prior to your planned awakening.
  • Take with or without food, however time to sleep onset may be delayed if taken with or soon after a meal.
  • This drug causes next-day somnolence. Use caution if driving or doing any other activities that require complete mental alertness, especially if you are older than 65 years old.
  • Do not consume alcohol or take with other CNS depressants.

Frequently asked questions

  • Quviviq vs. Ambien: How do they compare?
Share this Article
Latest News
Medical News

Colon cancer: Exercise as important as drugs in preventing recurrence

Jun 04, 2025
Alzheimer's: Common insomnia treatment may prevent brain damage
Cholesterol: Daily cup of beans may lower levels, improve heart health
Aging and longevity: What role might coffee play?
Seed oils: Omega-6 fatty acids may lower diabetes, heart disease risk
Type 2 diabetes: Sugary drinks may significantly raise risk
Related Drugs
Fidanacogene Elaparvovec
Cerave Anti-Itch
Centrum Adult
Crovalimab
Cyltezo Prefilled Syringe
Zepbound Pen
Mylanta One
Uretron Ds
Medihoney Wound And Burn Dressing
Lidotrode

Other drugs

Name Drug Class Updated
Fidanacogene Elaparvovec Drugs 03-Oct-2024
Cerave Anti-Itch Drugs 02-Oct-2024
Centrum Adult Drugs 02-Oct-2024
Crovalimab Drugs 02-Oct-2024
Cyltezo Prefilled Syringe Drugs 01-Oct-2024
Zepbound Pen Drugs 30-Sep-2024
Mylanta One Drugs 27-Sep-2024
Uretron Ds Drugs 27-Sep-2024
Medihoney Wound And Burn Dressing Drugs 26-Sep-2024
Lidotrode Drugs 26-Sep-2024
Libervant Drugs 26-Sep-2024
Moderna Covid-19 Drugs 25-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024

Categories

  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health

About US

Welcome to TheMediTary.Com

Our website provides reliable and up-to-date information on various medical topics. We empower individuals to take charge of their health by simplifying complex medical jargon and providing practical tips and advice. We prioritize the privacy and confidentiality of our users and welcome feedback to improve our services.

Website use data of FDA and other sources

DMCA.com Protection Status Truste Protection Status Trust Mark Protection Status
HONcode logo We comply with the HONcode standard for trustworthy health information.
Quick Link
  • About Us
  • Contact Us
  • Editorial Policy
  • Privacy Policy
  • Accessibility Policy
  • Terms & Conditions
  • Disclaimer
  • DMCA
  • Do Not Sell My Personal Information
  • Sitemap
  • Care Notes
  • Health Guide
  • Professional
Drugs
  • New Drugs
  • Medical Answers
  • Drugs A-Z
  • Drug Classes
  • Drug Dosage
  • Pill Identifier
  • Consumer Infor
  • Side Effects
  • Inactive Ingredients
  • Pregnancy Warnings
  • Patient Tips
  • Treatments
News
  • Latest News
  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health
Find US
  • Medium
  • Google Site
  • Blogspot
  • API
  • Reddit
  • Tumblr
  • Scoop.it
  • Substack
  • Wordpress
  • Wix
  • Behance

© 2025 TheMediTary.Com All rights reserved. Operated by