Drug Detail:Eflornithine (monograph) (Vaniqa)
Drug Class:
Usual Adult Dose for Hirsutism
Apply a thin layer to the affected area(s) of the face and under the chin twice a day allowing at least 8 hours between applications
Comments:
- This drug has only been studied on the face and adjacent involved areas under the chin and therefore usage should be limited to these areas of involvement.
- The treated area should not be washed for at least 4 hours.
- The patient should continue to use hair removal techniques in conjunction with this drug with application of this cream at least 5 minutes after hair removal.
Use: For the reduction of unwanted facial hair in women
Usual Pediatric Dose for Hirsutism
12 years or older: Apply a thin layer to the affected area(s) of the face and under the chin twice a day allowing at least 8 hours between applications
Comments:
- This drug has only been studied on the face and adjacent involved areas under the chin and therefore usage should be limited to these areas of involvement.
- The treated area should not be washed for at least 4 hours.
- The patient should continue to use hair removal techniques in conjunction with this drug with application of this cream at least 5 minutes after hair removal.
Use: For the reduction of unwanted facial hair in women
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Dose Adjustments
If skin irritation or intolerance develops, temporarily reduce frequency of application (e.g., once a day); if irritation continues, consider discontinuing treatment.
Precautions
Safety and efficacy have not been established in patients younger than 12 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- For topical dermatological use only; not for ophthalmic, oral, or intravaginal use.
- Rub in thoroughly
- Apply at least 5 minutes after using hair removal products
- Cosmetics or sunscreens may be applied over treated area once cream has dried.
Storage requirements:
- Store at room temperature; do not freeze.
General:
- Onset of improvement has been observed within 4 to 8 weeks of treatment; however, the condition may return to pretreatment levels 8 weeks after discontinuing treatment.
Patient advice:
- Continue using a hair removal method in conjunction with this drug.
