Drug Detail:Ganciclovir (monograph) (Zirgan)
Drug Class:
Usual Adult Dose for Herpes Simplex Dendritic Keratitis
Instill 1 drop in the affected eye 5 times a day (about every 3 hours while awake) until corneal ulcer heals, and then 1 drop 3 times a day for 7 days.
Use: For the treatment of acute herpetic keratitis (dendritic ulcers)
Usual Pediatric Dose for Herpes Simplex Dendritic Keratitis
2 years or older: Instill 1 drop in the affected eye 5 times a day (about every 3 hours while awake) until corneal ulcer heals, and then 1 drop 3 times a day for 7 days.
Use: For the treatment of acute herpetic keratitis (dendritic ulcers)
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Safety and efficacy have not been established in patients younger than 2 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- For topical ophthalmic use only
Storage requirements:
- Store at 15C to 25C (59F to 77F); do not freeze.
Patient advice:
- Do not wear contact lenses if you have signs/symptoms of herpetic keratitis or during therapy.
- Avoid contaminating the applicator tip with material from the eye, fingers, or any other source; do not touch the applicator tip to any surface.
- Contact physician if pain develops or redness, itching, or inflammation worsens.
