Usual Adult Dose for Dermatological Disorders

Apply to affected areas 2 times a day in the morning and at bedtime or as directed; if no improvement is seen after 2 months of therapy, discontinue use

Comments:

• Rub in well.

Use: For the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation

Usual Pediatric Dose for Dermatological Disorders

12 years and older:
Apply to affected areas 2 times a day in the morning and at bedtime or as directed; if no improvement is seen after 2 months of therapy, discontinue use

Comments:

• Rub in well.

Use: For the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Hypersensitivity to the active component or any of the ingredients

Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Test for skin sensitivity before using by applying a small amount to an unbroken patch of skin; check within 24 hours.
• Minor redness is not a contraindication, but where there is itching or vesicle formation or excessive inflammatory response further therapy is not advised. Close patient supervision is recommended.

Storage requirements:

• Store at 20C to 25C (68F to 77F); excursions permitted to 15C to 30C (59F to 86F).

General:

• This drug is a skin bleaching agent which may produce unwanted cosmetic effects if not used as directed.