Usual Adult Dose for Hereditary Angioedema

30 mg subcutaneously once, in the abdominal area; may repeat every 6 hours if response is inadequate or symptoms recur.

Maximum dose: 90 mg/day

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

No adjustment recommended

Precautions

CONTRAINDICATIONS: None

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Initial treatment should be given under the guidance of a physician in a medical institution. Patients may self-administer this drug after initial training.
• Attach the provided 25 gauge needle to the syringe hub and screw on securely. Do not use a different needle.
• Disinfect the injection site and administer by subcutaneous injection over at least 30 seconds.

• Store between 2 and 25C (36 to 77F). Do not freeze.
• Store in carton until time of administration.

• Advise patients to seek medical attention immediately if laryngeal symptoms occur.
• In case of insufficient relief or recurrence after self-treatment, patients should seek medical attention.
• Injection site reactions are reported in most patients after administration of this drug.
• Advise patients not to drive or use machinery if they feel tired or dizzy.

Frequently asked questions

• How long does Firazyr take to work?
• How do you administer/inject Firazyr?
• What is Firazyr used for?