Drug Detail:Icatibant (Icatibant [ eye-kat-i-bant ])
Drug Class: Hereditary angioedema agents
Usual Adult Dose for Hereditary Angioedema
30 mg subcutaneously once, in the abdominal area; may repeat every 6 hours if response is inadequate or symptoms recur.
Maximum dose: 90 mg/day
Renal Dose Adjustments
No adjustment recommended
Liver Dose Adjustments
No adjustment recommended
Precautions
CONTRAINDICATIONS: None
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Initial treatment should be given under the guidance of a physician in a medical institution. Patients may self-administer this drug after initial training.
- Attach the provided 25 gauge needle to the syringe hub and screw on securely. Do not use a different needle.
- Disinfect the injection site and administer by subcutaneous injection over at least 30 seconds.
Storage requirements:
- Store between 2 and 25C (36 to 77F). Do not freeze.
- Store in carton until time of administration.
Reconstitution/preparation techniques: The manufacturer product information should be consulted.
Patient advice:
- Advise patients to seek medical attention immediately if laryngeal symptoms occur.
- In case of insufficient relief or recurrence after self-treatment, patients should seek medical attention.
- Injection site reactions are reported in most patients after administration of this drug.
- Advise patients not to drive or use machinery if they feel tired or dizzy.
Frequently asked questions
- How long does Firazyr take to work?
- How do you administer/inject Firazyr?
- What is Firazyr used for?