Drug Detail:Vagistat-3 (Miconazole vaginal [ my-caw-nah-zole ])
Drug Class: Vaginal anti-infectives
Usual Adult Dose for Vaginal Candidiasis
Vaginal suppository:
1 day therapy: Insert 1200 mg suppository intravaginally at bedtime for 1 day.
3 day therapy: Insert 200 mg suppository intravaginally at bedtime for 3 days.
7 day therapy: Insert 100 mg suppository intravaginally at bedtime for 7 days.
Vaginal cream:
Intravaginally:
2% cream: Insert one applicatorful intravaginally at bedtime for 3 to 7 days.
4% cream: Insert one applicatorful intravaginally at bedtime for 3 days.
Topically: Apply to external vulvar area twice a day for up to 7 days, as needed.
Usual Adult Dose for Tinea Corporis
Topical cream, ointment, powder, spray, or tincture: Apply a thin layer to affected areas twice a day for 4 weeks.
Usual Adult Dose for Tinea Pedis
Topical cream, ointment, powder, spray, or tincture: Apply a thin layer to affected areas twice a day for 4 weeks.
Usual Adult Dose for Cutaneous Candidiasis
Topical cream, ointment, powder, or spray: Apply a thin layer to affected areas twice a day for 2 weeks.
Usual Adult Dose for Tinea Cruris
Topical cream, ointment, powder, or spray: Apply a thin layer to affected areas twice a day for 2 weeks.
Usual Adult Dose for Tinea Versicolor
Topical cream: Apply a thin layer to affected areas once a day.
Clinical and mycological clearing usually occur after 2 weeks of therapy.
Usual Pediatric Dose for Vaginal Candidiasis
12 years or older:
Vaginal suppository:
1 day therapy: Insert 1200 mg suppository intravaginally at bedtime for 1 day.
3 day therapy: Insert 200 mg suppository intravaginally at bedtime for 3 days.
7 day therapy: Insert 100 mg suppository intravaginally at bedtime for 7 days.
Vaginal cream:
Intravaginally:
2% cream: Insert one applicatorful intravaginally at bedtime for 3 to 7 days.
4% cream: Insert one applicatorful intravaginally at bedtime for 3 days.
Topically: Apply to external vulvar area twice a day for up to 7 days, as needed.
Usual Pediatric Dose for Tinea Corporis
2 years or older:
Topical cream, ointment, powder, spray, or tincture: Apply a thin layer to affected areas twice a day for 4 weeks.
Usual Pediatric Dose for Tinea Pedis
2 years or older:
Topical cream, ointment, powder, spray, or tincture: Apply a thin layer to affected areas twice a day for 4 weeks.
Usual Pediatric Dose for Cutaneous Candidiasis
2 years or older:
Topical cream, ointment, powder, or spray: Apply a thin layer to affected areas twice a day for 2 weeks.
Usual Pediatric Dose for Tinea Cruris
2 years or older:
Topical cream, ointment, powder, or spray: Apply a thin layer to affected areas twice a day for 2 weeks.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Patients should be advised to notify their physician if symptoms have not improved after completion of the treatment period and to discontinue use if increased signs of irritation or sensitivity (e.g., redness, itching, burning, blistering, swelling, oozing) develop.
Patients should be reevaluated and the diagnosis reconsidered if no improvement is noted after completion of the treatment period.
Patients should not use miconazole vaginal cream or suppositories if they have abdominal pain, fever, or offensive-smelling vaginal discharge.
Safety and effectiveness of the topical cream, topical ointment, topical powder, topical spray, and topical tincture have not been established in pediatric patients less than 2 years of age. Safety and effectiveness of the vaginal cream and vaginal suppository have not been established in pediatric patients less than 12 years of age.
Dialysis
Data not available
Other Comments
A physician should be consulted before initiating treatment of a vaginal condition. Some vaginal conditions have symptoms similar to a yeast infection, such as sexually transmitted disease (STD) or a tubal pregnancy.
In patients with frequent recurrent candidal vaginitis, it is important to consider factors that predispose to infection (other drugs and/or the use tight-fitting garments).
Patients should avoid sexual intercourse during use of intravaginal miconazole suppositories.
Frequently asked questions
- Why does Monistat burn/itch so bad?
- Monistat-1: white discharge and burning, is this normal?
- Do you wash Monistat out in the morning?
- How long do you have to lay down for after using Monistat?