Drug Detail:Moxifloxacin ophthalmic (Moxifloxacin ophthalmic [ mox-i-flox-a-sin ])
Drug Class: Ophthalmic anti-infectives
Usual Adult Dose for Bacterial Conjunctivitis
Moxeza(R): Instill 1 drop in the affected eye(s) twice a day.
Vigamox(R): Instill 1 drop in the affected eye(s) 3 times a day.
Duration of therapy: 7 days
Use: For the treatment of bacterial conjunctivitis due to susceptible strains of:
- Moxeza(R): Aerococcus viridans, Corynebacterium macginleyi, Enterococcus faecalis, Micrococcus luteus, Staphylococcus arlettae, S aureus, S capitis, S epidermidis, S haemolyticus, S hominis, S saprophyticus, S warneri, Streptococcus mitis, S pneumoniae, S parasanguinis, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Propionibacterium acnes, Chlamydia trachomatis
- Vigamox(R): Corynebacterium species, M luteus, S aureus, S epidermidis, S haemolyticus, S hominis, S warneri, S pneumoniae, Streptococcus (viridans group), Acinetobacter lwoffii, H influenzae, H parainfluenzae, C trachomatis
Usual Pediatric Dose for Bacterial Conjunctivitis
Moxeza(R):
- Aged 4 months or older: Instill 1 drop in the affected eye(s) twice a day.
Vigamox(R): Instill 1 drop in the affected eye(s) 3 times a day.
Duration of therapy: 7 days
Use: For the treatment of bacterial conjunctivitis due to susceptible strains of:
- Moxeza(R): A viridans, C macginleyi, E faecalis, M luteus, S arlettae, S aureus, S capitis, S epidermidis, S haemolyticus, S hominis, S saprophyticus, S warneri, S mitis, S pneumoniae, S parasanguinis, E coli, H influenzae, K pneumoniae, P acnes, C trachomatis
- Vigamox(R): Corynebacterium species, M luteus, S aureus, S epidermidis, S haemolyticus, S hominis, S warneri, S pneumoniae, Streptococcus (viridans group), A lwoffii, H influenzae, H parainfluenzae, C trachomatis
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
- Moxeza(R): None
- Vigamox(R): History of hypersensitivity to the active component, to other quinolones, or to any of the ingredients
Moxeza(R): Safety and efficacy have not been established in patients younger than 4 months.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- For topical ophthalmic use only (not for injection)
- Do not inject subconjunctivally; do not introduce directly into the anterior chamber of the eye.
Storage requirements:
- Store at 2C to 25C (36F to 77F).
Patient advice:
- Do not wear contact lenses if you have signs/symptoms of bacterial conjunctivitis.
- Avoid contaminating the applicator tip with material from the eye, fingers, or any other source; do not touch the applicator tip to any surface.
- Stop this drug and contact physician at first sign of rash or allergic reaction.
