Usual Adult Dose for Oral Thrush

Recommended dose: 400,000 to 600,000 units of the oral suspension orally 4 times a day
Duration of therapy: At least 48 hours after symptoms have disappeared and cultures demonstrate eradication

Comment:

• For the treatment of oral candidiasis, the suspension should be retained in the mouth for as long as possible before swallowing.

Usual Adult Dose for Intestinal Candidiasis

Recommended dose: 500,000 to 1,000,000 units of the tablet formulation orally 3 times a day
Duration of therapy: At least 48 hours after clinical cure

Use: Treatment of non-esophageal mucus membrane gastrointestinal candidiasis

Usual Pediatric Dose for Oral Thrush

1 month to 12 months:

• Recommended dose: 200,000 units of the oral suspension orally 4 times a day

• Recommended dose: 400,000 to 600,000 units of the oral suspension orally 4 times a day
• Duration of therapy: At least 48 hours after symptoms have disappeared and cultures demonstrate eradication

• Limited data in premature and low birth weight infants indicated efficacy with 100,000 units orally 4 times a day.
• Infants should avoid feeding for 5 to 10 minutes after administration.
• For the treatment of oral candidiasis, the suspension should be retained in the mouth for as long as possible before swallowing.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Patients should shake the oral suspension well prior to use, and the suspension should be administered by placing half of the dose in each side of the mouth with a dropper.

• The manufacturer product information should be consulted.

• This drug is fungistatic and fungicidal in yeasts and yeast-like fungi; it is not active against organisms lacking sterols in their cell membranes.

• Signs/symptoms of candidiasis (e.g., cultures)
• Hypersensitivity reactions

• Patients should continue treatment for at least 48 hours after symptoms disappear and/or cultures are negative for Candida albicans.
• Patients should be instructed to report signs/symptoms of hypersensitivity reactions.
• Patients should be told to immediately contact their healthcare providers if symptoms worsen and/or are not improved after 14 days.

Frequently asked questions

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