Drug Detail:Sodium ferric gluconate (monograph) (Ferrlecit)
Drug Class:
Usual Adult Dose for Anemia Associated with Chronic Renal Failure
10 mL in 100 mL 0.9% sodium chloride IV over 1 hour per dialysis session
OR
10 mL (125 mg elemental iron) undiluted slow IV (up to 12.5 mg elemental iron/min) per dialysis session
Comments:
- Most patients require a cumulative dose of 1000 mg of elemental iron administered over 8 dialysis sessions.
- Administer during the dialysis session itself.
- Doses over 125 mg elemental iron may have higher incidence or severity of adverse events.
Use: Treatment of iron deficiency anemia in patients with chronic kidney disease receiving hemodialysis who are receiving epoetin therapy.
Usual Pediatric Dose for Anemia Associated with Chronic Renal Failure
6 years and older: 0.12 mL/kg (1.5 mg/kg elemental iron) diluted in 25 mL 0.9% sodium chloride IV over 1 hour per dialysis session
Maximum dose: 125 mg elemental iron per dose
Comments:
- Administer during the dialysis session itself.
- Doses over 125 mg elemental iron may have higher incidence or severity of adverse events.
Use: Treatment of iron deficiency anemia in patients with chronic kidney disease receiving hemodialysis who are receiving epoetin therapy.
Renal Dose Adjustments
No adjustment recommended
Liver Dose Adjustments
Data not available
Precautions
Safety and efficacy have not been established in patients younger than 6 years.
Consult WARNINGS section for additional precautions.
Dialysis
See Usual Adult Dose or Usual Pediatric Dose
Other Comments
Administration advice:
- If diluted, use immediately.
- Administer diluted solution over 1 hour.
- Administer during dialysis.
IV compatibility:
- Do not mix with other medications.
- Compatibility with IV solutions other than 0.9% sodium chloride has not been established.
