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Home > Drugs > Selective immunosuppressants > Aubagio
Selective immunosuppressants

Aubagio

https://themeditary.com/drug/aubagio-56.html
Medically Reviewed by Philip Thornton, DipPharm TheMediTary.Com | Reviewed: Jul 10, 2023  Additional Content by TheMediTary.Com

Generic name: teriflunomide [ ter-i-floo-noe-mide ]

Drug class: Selective immunosuppressants

Dosage form: tablet, film coated

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Teriflunomide

Contents
Uses Warnings Before Taking Dosage Side effects Interactions FAQ

What is Aubagio?

Aubagio affects the immune system and reduces swelling and inflammation in the nervous system.

Aubagio is used to treat relapsing forms of multiple sclerosis in adults (including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease).

Aubagio is not a cure for MS.

Warnings

Do not use Aubagio if you are pregnant or may become pregnant. You will need to have a negative pregnancy test before starting this treatment. Tell your doctor right away if you become pregnant during treatment or within 2 years after your treatment ends.

Teriflunomide can cause severe liver problems. You should not use this medicine if you have severe liver disease or if you are also taking leflunomide (Arava). Tell your doctor if you have a history of liver disease.

Call your doctor at once if you have signs of liver problems: upper stomach pain, loss of appetite, dark urine, or jaundice (yellowing of the skin or eyes).

Your doctor may need to test your liver function up to 6 months before you start taking Aubagio, and then every month when you first start taking this medicine.

Teriflunomide can lower blood cells that help your body fight infections. This can make it easier for you to get sick from being around others who are ill. While using Aubagio, you may need blood tests every 6 months. Your blood pressure will also need to be checked often.

After you stop taking Aubagio, the drug could stay in your body for up to 2 years. You may need to be treated with other medications to help your body eliminate teriflunomide quickly. Follow your doctor's instructions.

How should I take Aubagio

Before you start treatment with Aubagio, your doctor may perform tests to make sure you do not have tuberculosis or other infections.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may take Aubagio with or without food.

Your blood pressure will need to be checked often.

Teriflunomide can lower your blood cell counts. Your blood will need to be tested often. Your treatment may be delayed based on the results.

After you stop taking Aubagio, you may need to be treated with other medicines to help your body eliminate teriflunomide quickly. If you do not undergo this drug elimination procedure, teriflunomide could stay in your body for up to 2 years. Follow your doctor's instructions.

You will also need to go through this drug elimination procedure if you plan to become pregnant after you stop taking this medicine.

Store at room temperature away from moisture and heat.

Dosing information

Usual Adult Dose for Multiple Sclerosis:

7 mg or 14 mg orally once a day

Use: Treatment of patients with relapsing forms of multiple sclerosis.

Detailed Aubagio dosage information
Aubagio Dosage information (more detail)

Before Taking

You should not use Aubagio if you are allergic to teriflunomide or leflunomide, or if:

  • you have severe liver disease; or

  • you are also taking leflunomide (Arava).

Do not use Aubagio if you are pregnant or may become pregnant You will need to have a negative pregnancy test before starting this treatment. Avoid getting pregnant until after you stop taking this medicine and undergo a "drug elimination" procedure to help rid your body of this medicine. Stop taking Aubagio and call your doctor right away if you miss a period or think you might be pregnant.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

  • liver or kidney disease;

  • high blood sugar;

  • high blood pressure;

  • skin problems when taking medicines;

  • a fever, or uncontrolled infections;

  • breathing problems;

  • tuberculosis; or

  • nerve problems, such as neuropathy.

Use birth control to prevent pregnancy while you are taking this medicine. After you stop taking Aubagio, continue using birth control until you have received blood tests to make sure the drug has been eliminated from your body.

If you become pregnant while taking Aubagio or within 2 years after you stop, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of teriflunomide on the baby.

If you are a man, use effective birth control to prevent pregnancy if your sex partner is able to get pregnant. After your treatment ends, keep using birth control until you have received the medications to help your body eliminate teriflunomide.

You should not breastfeed while using this medicine.

Aubagio pregnancy and breastfeeding warnings (more detail)

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Aubagio?

Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.

Do not receive a "live" vaccine while using Aubagio, and for at least 6 months after you stop taking it. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.

Aubagio side effects

Get emergency medical help if you have signs of an allergic reaction to Aubagio (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Stop using this medicine and call your doctor at once if you have:

  • numbness or tingling in your hands or feet that feels different from your MS symptoms;

  • trouble breathing, new or worsening cough with or without fever;

  • signs of infection - fever, chills, body aches, nausea, vomiting, feeling tired; or

  • liver problems - upper stomach pain, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes).

Common Aubagio side effects may include:

  • headache;

  • nausea, diarrhea;

  • thinning hair; or

  • abnormal liver function tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Aubagio Side Effects

What other drugs will affect Aubagio?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Your doctor may need to adjust the doses of any other medicines you take on a regular basis.

Many drugs can interact with teriflunomide. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Popular FAQ

Does Aubagio help with fatigue?
Should I take Aubagio in the morning or night?
How long do Aubagio side effects last?
Does Aubagio work in multiple sclerosis (MS)?

More FAQ

When best to take Aubagio, morning or night?
View more FAQ

More about Aubagio (Teriflunomide [ ter-i-floo-noe-mide ])

Dosage information
Aubagio Side Effects
Patient tips
During pregnancy
Aubagio Prescribing Information
Drug images
Side effects
Drug class: Selective immunosuppressants

Related treatment guides

Multiple Sclerosis
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Contents
Uses Warnings Before Taking Dosage Side effects Interactions FAQ
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