Hyoscyamine is used to treat many different stomach and intestinal disorders, including peptic ulcer and irritable bowel syndrome. It is also used to control muscle spasms in the bladder, kidneys, or digestive tract, and to reduce stomach acid.

Hyoscyamine is sometimes used to reduce tremors and rigid muscles in people with symptoms of Parkinson's disease.

Hyoscyamine is also used as a drying agent to control excessive salivation, runny nose, or excessive sweating.

Hyoscyamine may also be used for purposes not listed in this medication guide.

You should not use hyoscyamine if you have urination problems, a stomach or bowel obstruction, severe ulcerative colitis, glaucoma, or myasthenia gravis.

Hyoscyamine comes as a tablet, an extended-release (long-acting) capsule, and a liquid to take by mouth. The tablets and liquid are usually taken three or four times a day. The extended-release capsules are usually taken twice a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take hyoscyamine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the extended-release tablets whole; do not split, chew, or crush them.

Hyoscyamine controls symptoms associated with disorders of the GI tract, but it does not cure the disorders. Continue to take hyoscyamine even if you feel well. Do not stop taking hyoscyamine without talking to your doctor.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Always follow directions on the medicine label about giving hyoscyamine to a child.

Swallow an extended-release tablet whole and do not crush, chew, or break it.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Remove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet on your tongue and allow it to dissolve. Swallow several times as the tablet dissolves. You may drink water after the pill has completely dissolved.

Store at room temperature away from moisture and heat.

You should not use hyoscyamine if you are allergic to it, or if you have:

• a bladder obstruction or other urination problems;

• an enlarged prostate;

• a stomach or bowel obstruction (including paralytic ileus);

• severe ulcerative colitis, or toxic megacolon;

• glaucoma; or

• myasthenia gravis.

Hyoscyamine is not approved for use by anyone younger than 2 years old.

Tell your doctor if you have ever had:

• heart problems;

• high blood pressure;

• kidney disease;

• a colostomy or ileostomy;

• a thyroid disorder; or

• hiatal hernia with GERD (gastroesophageal reflux disease).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include headache, dizziness, dry mouth, trouble swallowing, nausea, vomiting, blurred vision, hot dry skin, and feeling restless or nervous.

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

Unless your doctor tells you otherwise, continue your normal diet.

Avoid taking antacids at the same time you take hyoscyamine. Antacids can make it harder for your body to absorb hyoscyamine. If you use an antacid, take it after you have taken hyoscyamine and eaten a meal.

Drinking alcohol with hyoscyamine can cause side effects.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Hyoscyamine can decrease sweating and you may be more prone to heat stroke.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Hyoscyamine may cause serious side effects. Stop using hyoscyamine and call your doctor at once if you have:

• anxiety, confusion, hallucinations, unusual thoughts or behavior;

• weakness, memory problems;

• slurred speech;

• problems with balance or muscle movement;

• diarrhea; o

• pounding heartbeats or fluttering in your chest.

Common side effects of hyoscyamine may include:

• dizziness, drowsiness, feeling weak or tired;

• decreased sweating, decreased urination;

• blurred vision;

• rash;

• dry mouth, decreased sense of taste;

• stomach pain, nausea, vomiting, bloating;

• diarrhea, constipation;

• headache;

• sleep problems (insomnia); or

• impotence, loss of interest in sex, or trouble having an orgasm.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tell your doctor about all your other medicines, especially:

• an antidepressant;

• medicine to treat mental illness;

• cold or allergy medicine (Benadryl and others);

• medicine to treat or prevent nausea and vomiting; or

• an MAO inhibitor--isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

This list is not complete. Other drugs may affect hyoscyamine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Keep all appointments with your doctor and the laboratory.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.