Lamisil is an antifungal medication that fights infections caused by fungus.

Lamisil tablets are used to treat infections caused by fungus that affect the fingernails or toenails.

Lamisil oral granules are used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old, though this medication is no longer available in the United States.

Some people taking Lamisil have developed severe liver damage leading to liver transplant or death.

Call your doctor at once if you have symptoms of liver damage, such as nausea, upper stomach pain, vomiting, loss of appetite, tiredness, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). These events can occur whether or not you have ever had liver problems before.

Before taking this medicine

You should not use Lamisil if you are allergic to terbinafine, or if you have:

• liver disease.

To make sure Lamisil is safe for you, tell your doctor if you have ever had:

• liver problems;

• kidney problems;

• weak immune system (caused by disease or by using certain medicine); or

• lupus.

It is not known whether terbinafine will harm an unborn baby. You should wait until after your pregnancy to start treating your nail or scalp infection with Lamisil. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Terbinafine can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

Take Lamisil exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You may take the tablet with or without food.

Lamisil granules should be sprinkled into a spoonful of pudding or mashed potatoes (do not mix with applesauce, fruit juice, or other fruit-based or acidic foods). Swallow this mixture right away without chewing. Do not save the mixture for later use.

Lamisil is usually taken for 6 weeks to treat scalp or fingernail infections, and for 12 weeks to treat a toenail infection.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antifungal medicine. Terbinafine will not treat a viral infection such as the flu or a common cold.

While using this medicine, you may need frequent blood tests.

It may take several months for your nails to return to their normal appearance after your treatment with Lamisil.

Store at room temperature away from moisture, heat, and light. Keep the oral granules in their sealed packet until you are ready to use.

You should not use Lamisil if you are allergic to terbinafine, or if you have:

• liver disease.

To make sure Lamisil is safe for you, tell your doctor if you have ever had:

• liver problems;

• kidney problems;

• weak immune system (caused by disease or by using certain medicine); or

• lupus.

It is not known whether terbinafine will harm an unborn baby. You should wait until after your pregnancy to start treating your nail or scalp infection with Lamisil. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Terbinafine can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include headache, dizziness, vomiting, stomach pain, rash, and increased urination.

Avoid coffee, tea, cola, energy drinks or other sources of caffeine while taking this medicine. Lamisil may prolong the effects of caffeine.

Avoid exposure to sunlight or tanning beds. Terbinafine can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Get emergency medical help if you have signs of an allergic reaction to Lamisil: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. This reaction may occur several weeks after you began using terbinafine.

Some people taking Lamisil have developed severe liver damage leading to liver transplant or death. It is not clear whether terbinafine actually caused the liver damage in these patients. In most cases, the patient had a serious medical condition before taking this medicine.

Call your doctor at once if you have symptoms of liver damage, such as nausea, upper stomach pain, vomiting, loss of appetite, tiredness, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). These events can occur whether or not you have ever had liver problems before.

Also call your doctor if you have:

• changes in your sense of taste or smell;

• depressed mood, sleep problems, lack of interest in daily activity, feeling anxious or restless;

• pale skin, easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;

• swelling, rapid weight gain, little or no urinating;

• blood in your urine or stools;

• weight loss due to taste changes or loss of appetite; or

• skin sores, butterfly-shaped skin rash on your cheeks and nose (worsens in sunlight).

Common Lamisil side effects may include:

• diarrhea, nausea, gas, stomach pain or upset;

• rash;

• headache; or

• abnormal liver function tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Other drugs may interact with terbinafine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.