Pyrukynd Taper Pack is used to treat low red blood cell counts caused by hemolytic anemia (early breakdown of red blood cells) in adults with pyruvate kinase deficiency.

Pyrukynd Taper Pack may also be used for purposes not listed in this medication guide.

Call your doctor at once if you have jaundice (yellowing of the skin or eyes), dark urine, dizziness, confusion, tiredness, or shortness of breath.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

You may take Pyrukynd Taper Pack with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

Do not share Pyrukynd Taper Pack with another person, even if they have the same symptoms you have.

Do not change your dose or stop using Pyrukynd Taper Pack without talking to your doctor. Your doctor will give you instructions for stopping this medicine.

Store this medicine in the original container at room temperature.

Tell your doctor if you have ever had:

• liver disease.

Tell your doctor if you are pregnant or breastfeeding.

Use the medicine as soon as you can, but skip the missed dose if you are more than 4 hours late for the dose. Do not use two doses at one time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Pyrukynd Taper Pack may cause serious side effects. Call your doctor at once if you have:

• jaundice (yellowing of the skin or eyes);

• dark urine;

• dizziness;

• confusion;

• tiredness; or

• shortness of breath.

Common side effects of Pyrukynd Taper Pack may include:

• flushing (sudden warmth, redness, or tingly feeling);

• breast swelling and tenderness;

• changes in sexual function;

• irregular heart rhythm;

• abnormal blood tests; or

• back or joint pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.

Other drugs may affect Pyrukynd Taper Pack, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.